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­Exfoliation syndrome and exfoliation glaucoma-associated LOXL1 variations are not involved in pigment dispersion syndrome and pigmentary glaucoma

机译:pigment色素沉着综合症和色素性青光眼不涉及剥脱综合征和与剥脱性青光眼有关的LOXL1变异

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摘要

PurposeSingle nucleotide polymorphisms (SNPs) in the LOXL1 gene have been implicated in exfoliation syndrome (XFS) and exfoliation glaucoma (XFG). We have shown that these SNPs are not associated with the primary glaucomas such as primary open-angle (POAG) glaucoma and primary angle-closure glaucoma (PACG). To further establish the specificity of LOXL1 SNPs for XFS and XFG, we determined whether these SNPs were involved in pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG).
机译:目的LOXL1基因中的单核苷酸多态性(SNPs)与剥脱综合征(XFS)和剥脱性青光眼(XFG)有关。我们已经证明这些SNP与原发性青光眼不相关,例如原发性开角型青光眼(POAG)和原发性闭角型青光眼(PACG)。为了进一步确定LOXL1 SNP对XFS和XFG的特异性,我们确定了这些SNP是否与色素弥散综合症(PDS)和色素性青光眼(PG)有关。

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