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Method for determining the risk of developing exfoliation syndrome or exfoliation glaucoma

机译:确定发生剥脱综合征或剥脱性青光眼的风险的方法

摘要

Based on allele information of single nucleotide polymorphisms (SNPs) in biological samples collected from subjects, SNPs selected from 12 core SNP groups described in Table 1 and pooled SNP groups described in Table 2 Step of measuring alleles for at least 30 SNPs in combination with the selected SNP group), based on the measurement results of the alleles, to obtain information on the onset risk of exfoliation syndrome or exfoliation glaucoma in the subject A subject's exfoliation syndrome or an information providing step of providing information for determining the development risk of exfoliation syndrome or exfoliation glaucoma of the subject based on the information acquired in the above, and the information acquisition step. Methods to help diagnose the risk of developing glaucoma. According to the method of the present invention, the SNP group of the present invention present in the sample derived from the subject is analyzed to determine the presence or absence of the risk of development of exfoliation syndrome or exfoliation glaucoma in the subject, and further, High and low can be predicted.
机译:根据从受试者收集的生物学样品中单核苷酸多态性(SNP)的等位基因信息,从表1中描述的12个核心SNP组和表2中描述的合并SNP组中选择SNP。选择的SNP组),基于等位基因的测量结果,获得有关受试者出现剥脱综合征或剥脱性青光眼的风险的信息。受试者的剥脱综合征或提供信息的步骤,用于提供确定剥脱综合征发生风险的信息根据以上获取的信息,以及信息获取步骤,对受试者的青光眼或剥脱性青光眼进行诊断。帮助诊断发生青光眼风险的方法。根据本发明的方法,分析源自受试者的样品中存在的本发明的SNP基团,以确定受试者中存在剥脱综合症或剥脱性青光眼的风险的存在或不存在,并且,高和低可以预测。

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