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Antifungal Substances from Streptomyces sp. A3265 Antagonistic to Plant Pathogenic Fungi

机译:链霉菌的抗真菌物质A3265与植物病原真菌拮抗

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摘要

In a previous study, we identified a Streptomyces sp., A3265, as exhibiting potent antifungal activity against various plant pathogenic fungi, including Botrytis cinerea, Colletotrichum gloeosporioides, and Rhizoctonia solani. This strain also exhibited a biocontrolling effect against ginseng root rot and damping-off disease, common diseases of ginseng and other crops. In this study, we isolated two antifungal substances responsible for this biocontrolling effect via Diaion HP-20 and Sephadex LH-20 column chromatography, medium pressure liquid chromatography, and high-performance liquid chromatography. These compounds were identified as guanidylfungin A and methyl guanidylfungin A by spectroscopic methods. These compounds exhibited potent antimicrobial activity against various plant pathogenic fungi as well as against bacteria.
机译:在以前的研究中,我们确定了一种链霉菌A3265,它对各种植物病原性真菌(包括灰葡萄孢(Botrytis cinerea),炭疽菌(Colletotrichum gloeosporioides)和茄根霉(Rhizoctonia solani))表现出有效的抗真菌活性。该菌株还显示出对人参根腐病和人参等作物常见病的​​抑制作用。在这项研究中,我们通过Diaion HP-20和Sephadex LH-20柱色谱,中压液相色谱和高效液相色谱分离了两种具有这种生物防治作用的抗真菌物质。通过光谱法将这些化合物鉴定为胍基真菌素A和甲基胍基真菌素A。这些化合物对各种植物致病真菌以及细菌均显示出有效的抗菌活性。

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