>Objective: This retrospective study analyzed the prognostic factors, the effect of different methods of treatments and the behavior of atypical meningioma. >Methods: Fourty one patients were diagnosed as atypical meningioma, among 273 patients who were given a diagnosis of meningioma in the period of 2002 to 2015. Age, gender, tumor location, Ki 67, Simpson grade and treatment received were analyzed. We studied the correlation between these factors with recurrence, overall survival rate and progression free survival. >Results: Mean patient ages was 57.8 ± 13.4 and mean follow up period was 63.9 ± 55.4 (moths). Mean overall survival rate and progression free survival rate are 73.6 ± 55.2 and 60.9 ± 52.6 (months)Better survival was observed for patients less than 50 years old but with no statistical significance (P = 0.096). And patients with total resection compared with subtotal resection also better survival rate but no statistical significance (P < 0.720). Patients with a tumor located in brain convexity, parasagittal and skull base also no statistical significance (P = 0.386). Progression-free survival showed a significant relationship with total resection compared with subtotal rescection (P = 0.008). >Conclusions: Independent prognostic factors affecting overall survival are not founded in our study. But we confirmed that Simpson grade was significant factor for statistically affect to progression free survival. Overall survival was not affected statistically by patient age, gender, tumor location, Ki 67, Simpson grade and treatment received in this study. This is may be due to most of patients are still alive. With long-term follow up period, it would be able to observe more independent prognostic factors clearly.
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