首页> 美国卫生研究院文献>NeuroImage : Clinical >Fully automated tissue segmentation of the prescription isodose region delineated through the Gamma knife plan for cerebral arteriovenous malformation (AVM) using fuzzy C-means (FCM) clustering
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Fully automated tissue segmentation of the prescription isodose region delineated through the Gamma knife plan for cerebral arteriovenous malformation (AVM) using fuzzy C-means (FCM) clustering

机译:通过模糊C均值(FCM)聚类的Gamma刀计划对脑动静脉畸形(AVM)划定的处方等剂量区域进行全自动组织分割

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摘要

BackgroundGamma knife radiosurgery (GKRS) is a common treatment for cerebral arterio-venous malformations (AVMs), particularly in cases where the malformation is deep-seated, large, or in eloquent areas of the brain. Unfortunately, these procedures can result in radiation injury to brain parenchyma. The fact that every AVM is unique in its vascular morphology makes it nearly impossible to exclude brain parenchyma from isodose radiation exposure during the formulation of a GKRS plan. Calculating the percentages of the various forms of tissue exposed to specific doses of radiation is crucial to understanding the clinical responses and causes of brain parenchyma injury following GKRS for AVM.
机译:背景伽玛刀放射外科(GKRS)是治疗脑动静脉畸形(AVM)的常用方法,尤其是在畸形深部,大或大脑雄辩的区域。不幸的是,这些程序可能导致对脑实质的放射损伤。每个AVM的血管形态都是独特的,这使得在制定GKRS计划期间几乎不可能从等剂量辐射中排除脑实质。计算暴露于特定剂量辐射下的各种形式的组织的百分比,对于了解AVM的GKRS后临床反应和脑实质损伤的原因至关重要。

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