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Analysis of Minimal Functions of Simian Virus 40 III. Evidence for Host Cell Repair of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40

机译：猿猴病毒40的最小功能分析。紫外线辐照猿猴病毒的致癌性和感染性的宿主细胞修复证据40

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The in vitro transforming capacity of simian virus 40 (SV40) for Syrian hamster cells is highly resistant to inactivation by UV light in comparison to infectivity. In the same cell system, we demonstrated a “host cell repair mechanism” sensitive to caffeine which is, to a large extent, responsible for the high resistance to UV inactivation of the transforming capacity of SV40. The survival of infectivity of UV-irradiated SV40 in CV-1 cells was also sensitive to caffeine, again indicating host cell repair. On the other hand, depression of normal cell DNA synthesis by hydroxyurea during the first 24 h postinfection only modestly reduced, and to a similar extent, the transforming capacity of UV-irradiated and nonirradiated SV40.

机译：与感染性相比，猿猴病毒40（SV40）对叙利亚仓鼠细胞的体外转化能力对紫外线的灭活具有很高的抵抗力。在同一细胞系统中，我们证明了对咖啡因敏感的“宿主细胞修复机制”，这在很大程度上对SV40转化能力的UV失活具有很高的抵抗力。 CV-1细胞中紫外线照射的SV40的感染力存活率也对咖啡因敏感，再次表明宿主细胞修复。另一方面，在感染后的最初24小时内，羟基脲对正常细胞DNA合成的抑制作用仅适度降低，并且以类似的程度降低了UV辐照和未辐照的SV40的转化能力。

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期刊名称 Journal of Virology
作者
N. H. Seemayer; V. Defendi;
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年(卷),期 1974(13),1
年度 1974
页码 36–41
总页数 6
原文格式 PDF
正文语种
中图分类人体病毒学（致病病毒）;病毒（滤过性病毒）;
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1. Analysis of Minimal Functions of Simian Virus 40 III. Evidence for “Host Cell Repair” of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40 [J] . N. H. Seemayer, V. Defendi Journal of Virology . 1974,第1期

机译：猿猴病毒40 III的最小功能分析。紫外线辐照硅藻病毒40的致癌性和感染性“宿主细胞修复”的证据
2. Analysis of Minimal Functions of Simian Virus 40 III. Evidence for “Host Cell Repair” of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40 [J] . N. H. Seemayer, V. Defendi Journal of Virology . 1974,第1期

机译：猿猴病毒40 III的最小功能分析。紫外线辐照硅藻病毒40的致癌性和感染性“宿主细胞修复”的证据
3. Analysis of Minimal Functions of Simian Virus 40 III. Evidence for “Host Cell Repair” of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40 [J] . N. H. Seemayer, V. Defendi Journal of Virology . 1974,第1期

机译：猿猴病毒40 III的最小功能分析。紫外线辐照硅藻病毒40的致癌性和感染性“宿主细胞修复”的证据
4. Computational Analysis of Nucleosome Positioning Signals in the Simian Virus 40 Chromatin [C] . Hongyan Zhao, Hong Yan International MultiConference of Engineers and Computer Scientists . 2009

机译：亚麻病毒40染色质中核心定位信号的计算分析
5. CHARACTERIZATION OF THE NUCLEAR MATRIX PREPARED FROM CELLS INFECTED WITH SIMIAN VIRUS 40 (REPLICATION). [D] . JONES, CLINTON JIMMIE. 1985

机译：从感染猿猴病毒40的细胞中制备的核基质的特性（复制）。
6. Control of Simian Virus 40 Gene Expression in Adenovirus-Simian Virus 40 Hybrid Viruses Synthesis of Hybrid Adenovirus 2-Simian Virus 40 RNA Molecules in Cells Infected with a Nondefective Adenovirus 2-Simian Virus 40 Hybrid Virus [O] . Michael N. Oxman, Myron J. Levin, Andrew M. Lewis Jr. 1974

机译：腺病毒-猿猴病毒40杂种病毒中猿猴病毒40基因表达的控制在感染无缺陷腺病毒2-猿猴病毒40杂种病毒的细胞中杂交腺病毒2-猿猴病毒40 RNA分子的合成
7. Analysis of Minimal Functions of Simian Virus 40 III. Evidence for “Host Cell Repair” of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40 [O] . N. H. Seemayer, V. Defendi 1974

机译：猿猴病毒40 III的最小功能分析。紫外线辐照硅藻病毒40的致癌性和感染性“宿主细胞修复”的证据

Analysis of Minimal Functions of Simian Virus 40 III. Evidence for Host Cell Repair of Oncogenicity and Infectivity of UV-Irradiated Simian Virus 40

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