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首页> 美国卫生研究院文献>Nutrients >Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China?
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Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China?

机译：现在是在中国Kashin-Beck病区停止施用富硒盐的适当时机吗？

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摘要

We aimed to identify significant factors of selenium (Se) nutrition of children in Kashin-Beck disease (KBD) endemic areas and non-KBD area in Shaanxi Province for providing evidence of whether it is the time to stop applying Se-enriched salt in KBD areas. A cross-sectional study contained 368 stratified randomly selected children aged 4–14 years was conducted with 24-h retrospective questionnaire based on a pre-investigation. Food and hair samples were collected and had Se contents determined with hydride generation atomic fluorescence spectrometry. Average hair Se content of 349.0 ± 60.2 ng/g in KBD-endemic counties was significantly lower than 374.1 ± 47.0 ng/g in non-KBD counties. It was significantly higher in the male children (365.2 ± 52.3 ng/g) than in the female (345.0 ± 62.2 ng/g, p = 0.002) and significantly higher in the 4.0–6.9 years group (375.2 ± 58.9 ng/g) than the 7.0–14.0 years group (347.0 ± 56.1 ng/g, p < 0.01). Gender, living area, Se intake without supplements, Se-enriched salt, oil source and protein intake were identified as significant factors of hair Se contents. Cereals, meat and milk were commonly included as significant food categories that mainly contributed to Se intake without supplement of the whole population. Balanced dietary structure without Se supplement could effectively enhance and maintain children’s Se nutrition. It may be the time to stop applying Se-enriched salt in KBD areas in Shaanxi Province.
机译：我们旨在确定陕西省Kashin-Beck病（KBD）流行地区和非KBD流行地区儿童硒（Se）营养的重要因素，以提供是否应该停止在KBD中使用富硒盐的证据地区。一项横断面研究基于前期调查，采用24小时回顾性调查表对368名4-14岁的分层分层随机选择的儿童进行了调查。收集食物和头发样品，并用氢化物发生原子荧光光谱法测定硒含量。 KBD流行县的平均头发硒含量为349.0±60.2 ng / g，显着低于非KBD县的374.1±47.0 ng / g。男性儿童（365.2±52.3 ng / g）显着高于女性（345.0±62.2 ng / g，p = 0.002），而4.0-6.9岁组（375.2±58.9 ng / g）显着更高比7.0–14.0年组（347.0±56.1 ng / g，p <0.01）。性别，生活区，无补充硒摄入，富硒盐，油源和蛋白质摄入被确定为头发硒含量的重要因素。谷物，肉类和牛奶通常被列为重要的食物类别，主要导致硒的摄入而没有补充整个人群。不含硒补充剂的均衡饮食结构可以有效增强和维持儿童的硒营养。现在可能是在陕西省KBD地区停止使用富硒盐的时候了。

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