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TAMable tumor-associated macrophages in response to innate RNA sensing

机译：TAMable肿瘤相关巨噬细胞对先天RNA感应的响应

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摘要

Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to become an additional antitumor effector through polyI:C response.

机译：PolyI：C（病毒dsRNA类似物）的抗肿瘤作用已被归因于树突状细胞（DC）的成熟活性，该活性驱动抗肿瘤NK细胞，DC交叉呈递，细胞毒性T淋巴细胞和许多IFN诱导型基因。根据最近的一篇论文，发现浸润肿瘤的M2巨噬细胞通过polyI：C反应成为一种额外的抗肿瘤效应子。

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期刊名称 Oncoimmunology
作者
Tsukasa Seya; Hiroaki Shime; Misako Matsumoto;
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年(卷),期 2012(1),6
年度 2012
页码 1000–1001
总页数 2
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专利

1. An Investigation of Innate Immune Response of Human Blood Macrophage to Sense and Antisense dsRNA [J] . Nasrin Mohajeri, Zarrin Sharifnia, Mojgan Bandehpour, Trends in Peptide and Protein Sciences . 2016,第1期

机译：人血巨噬细胞对有义和反义dsRNA的天然免疫反应的研究
2. Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells [J] . Lei Miao, Jingjing Qi, Qi Zhao, Theranostics . 2020,第2期

机译：靶向肿瘤相关巨噬细胞中的刺痛途径调节胃癌细胞的先天免疫感测
3. SRNA_59370 IN PSEUDOMONAS AERUGINOSA OUTER MEMBRANE VESICLES INHIBITS THE INNATE IMMUNE RESPONSE OF MACROPHAGES AND EPITHELIAL CELLS [J] . Holden V. I, Li Z., Barnaby R. L., Pediatric Pulmonology . 2019,第Suppla2期

机译：铜绿假单胞菌外膜囊泡的SRNA_59370抑制巨噬细胞和上皮细胞的先天免疫应答
4. Therapeutic in vivo RNAi-based nanoparticle silencing in lung tumor-associated macrophages [C] . Joao Conde, Chenchen Bao, Yeqi Tan, Society for Biomaterials annual meeting and exposition . 2015

机译：体内治疗基于RNAi的纳米粒子沉默与肺肿瘤相关的巨噬细胞。
5. Targeted siRNA Delivery Strategy with Water-in-Oil-in-Water Multiple Emulsion for Modulation of Tumor-Associated Macrophage Polarity in Immunotherapy of Cancer [D] . Oka, Adwait 2015

机译：有针对性的siRNA传递策略与水包油中水多乳液调节肿瘤相关巨噬细胞极性在免疫疗法中的癌症。
6. Targeting the STING pathway in tumor-associated macrophages regulates innate immune sensing of gastric cancer cells [O] . Lei Miao, Jingjing Qi, Qi Zhao, 2020

机译：靶向肿瘤相关巨噬细胞中的STING通路可调节胃癌细胞的先天免疫感知
7. TAMable tumor-associated macrophages in response to innate RNA sensing [O] . Seya, Tsukasa, Shime, Hiroaki, Matsumoto, Misako 2012

机译：TAMable肿瘤相关巨噬细胞对先天RNA感应的响应

TAMable tumor-associated macrophages in response to innate RNA sensing

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