Genetics and immunology: reinvigorated

机译：遗传学和免疫学：焕发活力

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Immune checkpoint blockade therapy is changing oncology by improving the outcome of patients with advanced malignancies. Our research has revealed the genetic features of tumors present in patients who initiate a successful antitumor immune response and derive clinical benefit from immune checkpoint blockade therapy versus non-responders.

机译：免疫检查站封锁疗法正在通过改善晚期恶性肿瘤患者的预后来改变肿瘤学。我们的研究表明，与无反应者相比，能够成功启动抗肿瘤免疫反应并从免疫检查点封锁疗法获得临床益处的患者中，存在肿瘤的遗传特征。

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期刊名称 Oncoimmunology
作者
Alexandra Snyder; Vladimir Makarov; Matthew Hellmann; Naiyer Rizvi; Taha Merghoub; Jedd D Wolchok; Timothy A Chan;
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年(卷),期 2015(4),10
年度 2015
页码 e1029705
总页数 2
原文格式 PDF
正文语种
中图分类
关键词
biomarkers cancer CTLA-4 genomics immunomonitoring immunotherapy mutation new targets PD-1;

机译：生物标志物;癌症;CTLA-4;基因组学;免疫监测;免疫疗法;突变;新靶标;PD-1;

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1. Genetics and immunology: reinvigorated [J] . Snyder Alexandra, Makarov Vladimir, Hellmann Matthew, Oncoimmunology. . 2015,第10期

机译：遗传学和免疫学：焕发活力
2. Interleukin-12 Producing Genetically Engineered Macrophages to Reinvigorate Antitumor Immunity Against Advanced Gastrointestinal Cancer [J] . Labadie Kevin P., Kreuser Shannon A., Brempelis Katherine J., Journal of the American College of Surgeons . 2019,第4Suppla1期

机译：白细胞介素-12产生遗传工程巨噬细胞，以重新抗胃肠癌症的抗肿瘤免疫力
3. Reinvigorating Genetically Modified Crops [J] . ROBERT L. PAARLBERG Issues in Science and Technology . 2003,第3期

机译：重振转基因作物
4. Immunology and Genetics: Phenotypic, Genetic and Epigenetic Variation of Bovine Immune Responses and Disease Resistance [C] . Bonnie A. Mallard Annual Conference of American Association of Bovine Practitioners . 2007

机译：免疫学和遗传学：表型，遗传和表观遗传变异牛免疫应答和抗病性
5. Avian immunology, immunogenetics, and host immune response to Salmonella enterica serovar Enteritidis infection in chickens [D] . Cheeseman, Jennifer Helen 2007

机译：禽对鸡肠炎沙门氏菌肠炎沙门氏菌感染的免疫学，免疫遗传学和宿主免疫反应
6. Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology [O] . Stefan H. E. Kaufmann 2020

机译：针对结核病的疫苗接种：通过免疫学指导的分子遗传学改良卡介苗
7. Genetics and immunology: reinvigorated [O] . Alexandra Snyder, Vladimir Makarov, Matthew Hellmann, 2015

机译：遗传和免疫学：重新发明
8. Selected Contributions to the Literature of Blood Groups and Immunology. The Translation and Reproduction of Scientific Treatises in Blood Group Immunology. 1963-1973. A Monograph [R] . Camp, F. R., Ellis, F. R., Conte, N. F. 1973

机译：对血型和免疫学文献的选择贡献。血型免疫学科学论文的翻译与再现。 1963-1973。专着

Genetics and immunology: reinvigorated

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