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Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization

机译：关节参与青少年特发性关节炎的模式和疾病进程的预测：多层非负矩阵分解的前瞻性研究

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BackgroundJoint inflammation is the common feature underlying juvenile idiopathic arthritis (JIA). Clinicians recognize patterns of joint involvement currently not part of the International League of Associations for Rheumatology (ILAR) classification. Using unsupervised machine learning, we sought to uncover data-driven joint patterns that predict clinical phenotype and disease trajectories.

机译：背景关节发炎是青少年特发性关节炎（JIA）的共同特征。临床医生认识到目前不属于国际风湿病协会联盟（ILAR）分类的联合参与模式。使用无监督机器学习，我们试图发现预测临床表型和疾病轨迹的数据驱动关节模式。

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期刊名称 PLoS Medicine
作者
Simon W. M. Eng; Florence A. Aeschlimann; Mira van Veenendaal; Roberta A. Berard; Alan M. Rosenberg; Quaid Morris; Rae S. M. Yeung;
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年(卷),期 2019(16),2
年度 2019
页码 e1002750
总页数 22
原文格式 PDF
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中图分类基础医学;
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专利

1. Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization [J] . Simon W. M. Eng, Florence A. Aeschlimann, Mira van Veenendaal, PLoS Medicine . 2019,第2期

机译：联合参与青少年特发性关节炎的模式和疾病进程的预测：多层非负矩阵分解的前瞻性研究
2. Finding specific 10-joint Juvenile Arthritis Disease Activity Score (JADAS10) and clinical JADAS10 cut-off values for disease activity levels in non-systemic juvenile idiopathic arthritis: a Finnish multicentre study [J] . Backstrom Maria, Tynjala Pirjo, Ylijoki Heikki, Rheumatology . 2016,第4期

机译：在非系统性幼年特发性关节炎中查找特定的10关节青少年关节炎疾病活动评分（JADAS10）和临床JADAS10临界值以了解疾病活动水平：一项芬兰多中心研究
3. Growth patterns in early juvenile idiopathic arthritis: Results from the Childhood Arthritis Prospective Study (CAPS) [J] . Flora McErlane, Roberto Carrasco, Lianne Kearsley-Fleet, Seminars in Arthritis and Rheumatism . 2018,第1期

机译：早期幼年特发性关节炎的生长模式：儿童关节炎前瞻性研究（帽）的结果
4. 3D Facial Asymmetry in Patients with Juvenile Idiopathic Arthritis involving the Temporo-Mandibular Joint [C] . S. Demant, N.V. Hermann, T.A. Darvann, International Congress on Cleft Lip and Palate and Related Craniofacial Anomalies . 2009

机译：少年特发性关节炎患者的3D面部不对称性涉及颞下颌关节
5. The Use of S100 Proteins Testing in Juvenile Idiopathic Arthritis and Autoinflammatory Diseases in a Pediatric Clinical Setting: A Retrospective Analysis [D] . Aljaberi, Najla. 2020

机译：在儿科临床环境中使用S100蛋白在幼年作用关节炎和自身炎症疾病中的使用：回顾性分析
6. Treatment prescribing patterns in a cohort of patients with juvenile idiopathic arthritis (JIA). Data from the childhood arthritis prospective study (CAPS) [O] . Rebecca Davies, Roberto Carrasco, Helen E Foster, 2014

机译：少年特发性关节炎（JIA）患者队列中的治疗处方模式。儿童关节炎前瞻性研究（CAPS）的数据
7. SAT0499 ORAL MICROBIOME IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITISIN RELATION TO DISEASE STATUS, TEMPOROMANDIBULAR JOINT ARTHRITIS AND MEDICATION: A NORWEGIAN 2-YEAR PROSPECTIVE STUDY [O] . Paula Frid, Josefine Halbig, Divyashri Baraniya, 2019

机译：SAT0499口腔微生物微生物菌与疾病状况，颞下颌关节炎和药物有关的儿童：挪威2年的前瞻性研究

Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization

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