首页> 美国卫生研究院文献>Revista Brasileira de Ortopedia >BIOMECHANICS AND HISTOLOGICAL ANALYSIS IN RABBIT FLEXOR TENDONS REPAIRED USING THREE SUTURE TECHNIQUES (FOUR AND SIX STRANDS) WITH EARLY ACTIVE MOBILIZATION
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BIOMECHANICS AND HISTOLOGICAL ANALYSIS IN RABBIT FLEXOR TENDONS REPAIRED USING THREE SUTURE TECHNIQUES (FOUR AND SIX STRANDS) WITH EARLY ACTIVE MOBILIZATION

机译:早期主动动员的三种缝合技术(四级和六级)修复的兔屈肌腱的生物力学和组织学分析

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摘要

Objective: Analyzing suture time, biomechanics (deformity between the stumps) and the histology of three groups of tendinous surgical repair: Brazil-2 (4-strands) which the end knot (core) is located outside the tendon, Indiana (4-strands) and Tsai (6-strands) with sutures technique which the end knot (core) is inner of the tendon, associated with early active mobilization. Methods: The right calcaneal tendons (plantar flexor of the hind paw) of 36 rabbits of the New Zealand breed (Oryctolagus cuniculus) were used in the analysis. This sample presents similar size to human flexor tendon that has approximately 4.5 mm (varying from 2mm). The selected sample showed the same mass (2.5 to 3kg) and were male or female adults (from 8 ½ months). For the flexor tendons of the hind paws, sterile and driven techniques were used in accordance to the Committee on Animal Research and Ethics (CETEA) of the University of the State of Santa Catarina (UDESC), municipality of Lages, in Brazil (protocol # 1.33.09). Results: In the biomechanical analysis (deformity) carried out between tendinous stumps, there was no statistically significant difference (p>0.01). There was no statistical difference in relation to surgical time in all three suture techniques with a mean of 6.0 minutes for Tsai (6- strands), 5.7 minutes for Indiana (4-strands) and 5.6 minutes for Brazil (4-strands) (p>0.01). With the early active mobility, there was qualitative and quantitative evidence of thickening of collagen in 38.9% on the 15th day and in 66.7% on the 30th day, making the biological tissue stronger and more resistant (p=0.095). Conclusion: This study demonstrated that there was no histological difference between the results achieved with an inside or outside end knot with respect to the repaired tendon and the number of strands did not affect healing, vascularization or sliding of the tendon in the osteofibrous tunnel, which are associated with early active mobility, with the repair techniques applied.
机译:目的:分析三组腱手术修复的缝合时间,生物力学(残端之间的变形)和组织学:末端结(芯)位于腱外的巴西2号(4股),印第安纳州(4股) )和蔡(6股)缝合技术,其末端结(芯)位于肌腱内部,与早期主动动员相关。方法:采用新西兰兔(Oryctolagus cuniculus)36只兔的右跟骨肌腱(后爪pa屈)进行分析。该样品的大小与人体屈肌腱相似,约为4.5毫米(从2毫米变化)。所选择的样品显示相同的质量(2.5至3kg),并且是成年男性或女性(8.5个月大)。对于后爪的屈肌腱,根据巴西拉格市圣卡塔琳娜州大学(UDESC)的动物研究与伦理委员会(CETEA)使用的无菌和驱动技术(协议编号: 1.33.09)。结果:在肌腱残端之间进行的生物力学分析(变形)中,差异无统计学意义(p> 0.01)。三种缝合技术在手术时间方面均无统计学差异,Tsai(6股)平均6.0分钟,印第安纳州(4股)5.7分钟,巴西(4股)5.6分钟(p > 0.01)。在早期活动性活动的情况下,有定性和定量的证据表明胶原蛋白在第15天增加了38.9%,在第30天增加了66.7%。生物组织更强壮和更有抵抗力(p = 0.095)。结论:这项研究表明,对于修复的肌腱而言,内结或外结的结果之间没有组织学差异,并且股数不影响骨纤维隧道中肌腱的愈合,血管化或滑动,因此与早期的主动出行相关,并采用了修复技术。

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