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首页> 美国卫生研究院文献>The Scientific World Journal >The Square Curve Paradigm for Research in Alternative Complementary and Holistic Medicine: A Cost-Effective Easy and Scientifically Valid Design for Evidence-Based Medicine and Quality Improvement
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The Square Curve Paradigm for Research in Alternative Complementary and Holistic Medicine: A Cost-Effective Easy and Scientifically Valid Design for Evidence-Based Medicine and Quality Improvement

机译：替代医学补充医学和整体医学研究的平方曲线范式：循证医学和质量改进的经济有效简便且科学有效的设计

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In this paper we present a new research paradigm for alternative, complementary, and holistic medicine — a low-cost, effective, and scientifically valid design for evidence-based medicine. Our aim is to find the simplest, cheapest, and most practical way to collect data of sufficient quality and validity to determine: (1) which kinds of treatment give a clinically relevant improvement to quality of life, health, and/or functionality; (2) which groups of patients can be aided by alternative, complementary, or holistic medicine; and (3) which therapists have the competence to achieve the clinically relevant improvements. Our solution to the problem is that a positive change in quality of life must be immediate to be taken as caused by an intervention. We define “immediate” as within 1 month of the intervention. If we can demonstrate a positive result with a group of chronic patients (20 or more patients who have had their disease or state of suffering for 1 year or more), who can be significantly helped within 1 month, and the situation is still improved 1 year after, we find it scientifically evidenced that this cure or intervention has helped the patients. We call this characteristic curve a “square curve”. If a global, generic, quality-of-life questionnaire like QOL5 or, even better, a QOL-Health-Ability questionnaire (a quality-of-life questionnaire combined with a self-evaluated health and ability to function questionnaire) is administered to the patients before and after the intervention, it is possible to document the effect of an intervention to a cost of only a few thousand Euros/USD. A general acceptance of this new research design will solve the problem that there is not enough money in alternative, complementary, and holistic medicine to pay the normal cost of a biomedical Cochrane study. As financial problems must not hinder the vital research in nonbiomedical medicine, we ask the scientific community to accept this new research standard.
机译：在本文中，我们提出了一种替代，补充和整体医学的新研究范式-一种基于证据的医学的低成本，有效和科学有效的设计。我们的目标是找到最简单，最便宜，最实用的方法来收集具有足够质量和有效性的数据，以确定：（1）哪种治疗方法可以改善生活质量，健康状况和/或功能，并在临床上起到相关作用； （2）哪些患者可以通过替代，补充或整体药物来辅助治疗； （3）哪些治疗师有能力取得与临床相关的改善。我们解决该问题的方法是，必须立即采取干预措施，使生活质量发生积极变化。我们将“立即”定义为干预后1个月内。如果我们能够对一组慢性病患者（20例或更多患有疾病或患病状态达一年或以上的患者）显示出积极的结果，那么他们将在1个月内获得显着帮助，并且情况仍将得到改善1一年后，我们发现科学证明这种治疗或干预措施对患者有帮助。我们将此特征曲线称为“方形曲线”。如果要使用全球通用的生活质量问卷（例如QOL5），甚至更好的是QOL健康能力问卷（生活质量问卷与自我评估的健康和功能能力问卷相结合），干预前后的患者，只需花费几千欧元/美元即可记录干预的效果。这项新研究设计的普遍接受将解决以下问题：替代医学，补充医学和整体医学没有足够的资金来支付生物医学Cochrane研究的正常费用。由于财务问题一定不能阻碍非生物医学领域的重要研究，因此我们要求科学界接受这一新的研究标准。

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