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首页> 外文期刊>ScientificWorldJournal >The Square Curve Paradigm for Research in Alternative, Complementary, and Holistic Medicine: A Cost-Effective, Easy, and Scientifically Valid Design for Evidence-Based Medicine and Quality Improvement
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The Square Curve Paradigm for Research in Alternative, Complementary, and Holistic Medicine: A Cost-Effective, Easy, and Scientifically Valid Design for Evidence-Based Medicine and Quality Improvement

机译：替代，互补和整体医学研究的方形曲线范式：用于基于证据的药物和质量改进的成本效益，简单，科学有效的设计

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In this paper we present a new research paradigm for alternative, complementary, and holistic medicine — a low-cost, effective, and scientifically valid design for evidence-based medicine. Our aim is to find the simplest, cheapest, and most practical way to collect data of sufficient quality and validity to determine: (1) which kinds of treatment give a clinically relevant improvement to quality of life, health, and/or functionality; (2) which groups of patients can be aided by alternative, complementary, or holistic medicine; and (3) which therapists have the competence to achieve the clinically relevant improvements. Our solution to the problem is that a positive change in quality of life must be immediate to be taken as caused by an intervention. We define “immediate” as within 1 month of the intervention. If we can demonstrate a positive result with a group of chronic patients (20 or more patients who have had their disease or state of suffering for 1 year or more), who can be significantly helped within 1 month, and the situation is still improved 1 year after, we find it scientifically evidenced that this cure or intervention has helped the patients. We call this characteristic curve a “square curve”. If a global, generic, quality-of-life questionnaire like QOL5 or, even better, a QOL-Health-Ability questionnaire (a quality-of-life questionnaire combined with a self-evaluated health and ability to function questionnaire) is administered to the patients before and after the intervention, it is possible to document the effect of an intervention to a cost of only a few thousand Euros/USD. A general acceptance of this new research design will solve the problem that there is not enough money in alternative, complementary, and holistic medicine to pay the normal cost of a biomedical Cochrane study. As financial problems must not hinder the vital research in nonbiomedical medicine, we ask the scientific community to accept this new research standard.
机译：在本文中，我们为替代，互补和整体医学提供了新的研究范式 - 一种用于循证医学的低成本，有效和科学有效的设计。我们的目标是找到最简单，最便宜，最实用的方法来收集足够的质量和有效性的数据，以确定：（1）哪种治疗在临床上有关的生活质量，健康和/或功能的临床相关的改善; （2）哪些患者可以通过替代，互补或整体医学援助; （3）哪位治疗师有能力实现临床相关的改进。我们对问题的解决方案是，生活质量的积极变化必须立即被视为由干预造成的。我们在干预的1个月内定义“立即”。如果我们可以证明一组慢性患者（20名或更多患者的疾病或患有1年或更长时间的患者）的阳性结果，那么在1个月内可以大大帮助，情况仍然改善1一年后，我们发现它科学证明了这种治疗或干预有助于患者。我们称之为这个特征曲线“方形曲线”。如果像QOL5一样的全球，通用，生活质量问卷，甚至更好地，QOL健康能力问卷（寿命质量问卷与自我评价的健康和功能调查问卷的能力）进行管理干预前后的患者，可以将干预的效果记录到只有几千欧元/美元的成本。普遍接受这项新的研究设计将解决问题，即在替代，互补和整体医学中没有足够的资金来支付生物医学Cochrane研究的正常成本。由于财务问题不妨碍非生物医学的重要研究，我们要求科学界接受这一新的研究标准。

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