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首页> 美国卫生研究院文献>Sensors (Basel Switzerland) >Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study
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Noninvasive Assessment of Aortic Pulse Wave Velocity by the Brachial Occlusion-Cuff Technique: Comparative Study

机译：肱动脉闭塞袖带法无创评估主动脉脉搏波速度：对比研究

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Cardiovascular diseases are one of most frequent cause of morbidity and mortality in the world. There is an emerging need for integrated, non-invasive, and easy-to-use clinical tools to assess accurately cardiovascular system primarily in the preventative medicine. We present a novel design for a non-invasive pulse wave velocity (PWV) assessment method integrated in a single brachial blood pressure monitor allowing for up to 100 times more sensitive recording of the pressure pulsations based on a brachial occlusion-cuff (suprasystolic) principle. The monitor prototype with built-in proprietary method was validated with a gold standard reference technique SphygmoCor VX device. The blood pressure and PWV were assessed on twenty-five healthy individuals (9 women, age (37 ± 13) years) in a supine position at rest by a brachial cuff blood pressure monitor prototype, and immediately re-tested using a gold standard method. PWV using our BP monitor was (6.67 ± 0.96) m/s compared to PWV determined by SphygmoCor VX (6.15 ± 1.01) m/s. The correlation between methods using a Pearson’s correlation coefficient was r = 0.88 (p < 0.001). The study demonstrates the feasibility of using a single brachial cuff build-in technique for the assessment of the arterial stiffness from a single ambulatory blood pressure assessment.
机译：心血管疾病是世界上发病率和死亡率最常见的原因之一。对集成的，非侵入性的和易于使用的临床工具的需求正在出现，主要是在预防医学中准确评估心血管系统。我们提出了一种新颖的无创脉搏波速度（PWV）评估方法设计，该方法集成在单个臂式血压监护仪中，基于臂丛袖套（收缩压）原理，可以使压力脉动的敏感记录提高100倍。具有内置专有方法的显示器原型已通过金标准参考技术SphygmoCor VX设备进行了验证。通过臂袖血压监测仪原型对卧位休息的25名健康个体（9名女性，年龄（37±13）岁）的血压和PWV进行了评估，并立即使用金标准方法进行了重新测试。与通过SphygmoCor VX测定的PWV（6.15±1.01）m / s相比，使用我们的BP监护仪的PWV为（6.67±0.96）m / s。使用Pearson相关系数的方法之间的相关系数为r = 0.88（p <0.001）。这项研究表明，使用单臂腕套内置技术从单次动态血压评估中评估动脉僵硬度的可行性。

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