首页> 美国卫生研究院文献>Stem Cell Research Therapy >Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering

机译:沃顿氏胶冻包埋在藻酸盐水凝胶中且未添加生长因子的间充质基质/干细胞的软骨诱导:软骨组织工程的另一种干细胞来源

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摘要

BackgroundDue to their intrinsic properties, stem cells are promising tools for new developments in tissue engineering and particularly for cartilage tissue regeneration. Although mesenchymal stromal/stem cells from bone marrow (BM-MSC) have long been the most used stem cell source in cartilage tissue engineering, they have certain limits. Thanks to their properties such as low immunogenicity and particularly chondrogenic differentiation potential, mesenchymal stromal/stem cells from Wharton’s jelly (WJ-MSC) promise to be an interesting source of MSC for cartilage tissue engineering.
机译:背景由于干细胞的内在特性,它们是组织工程新发展尤其是软骨组织再生的有前途的工具。尽管长期以来,骨髓间充质基质/干细胞(BM-MSC)一直是软骨组织工程中最常用的干细胞来源,但它们仍具有一定的局限性。沃顿氏胶冻(WJ-MSC)的间充质基质/干细胞由于其低免疫原性和特别的成软骨分化潜能等特性,有望成为软骨组织工程中MSC的一个有趣来源。

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