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首页> 美国卫生研究院文献>Tobacco Control >Passive smoking in the home: plasma cotinine concentrations in non-smokers with smoking partners
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Passive smoking in the home: plasma cotinine concentrations in non-smokers with smoking partners

机译：在家中被动吸烟：有吸烟伙伴的非吸烟者血浆可替宁浓度

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BACKGROUND—Risks of lung cancer and of heart disease attributable to passive smoking have been evaluated mainly in non-smokers married to smokers, but there has been little quantitative assessment of the extent of exposure in marriage partners as indicated by markers of inhaled smoke dose.
OBJECTIVE—To relate plasma cotinine concentrations in non-smoking English adults to the smoking behaviour of their partners and to demographic and other factors.
DATA—Population survey. Data from two years (1994 and 1996) of the Health Survey for England.
MAIN OUTCOME MEASURES—Plasma cotinine concentrations in non-smoking adults married to or cohabiting with a partner.
RESULTS—There was a strong dose-response relation between cotinine concentrations in non-smoking adults and the smoking behaviour of their partners, rising from a geometric mean of 0.31 ng/ml in those with non-smoking partners to 1.99 ng/ml in those whose partners smoked 30 or more cigarettes per day. In addition, exposure was greater in men, in the autumn and winter, and in those living in more disadvantaged circumstances, and there was an increasing gradient of exposure from the south to the north of the country. On average, cotinine concentrations in non-smokers with a smoking partner were 0.6-0.7% of those in cigarette smokers.
CONCLUSIONS—If cotinine is taken as a measure of risk relevant dose, the implied increase in risk of lung cancer in non-smokers with smoking partners is consistent with the risk observed in epidemiological studies. Smoking by partners in the home is a major source of non-smoking adults' exposure to passive smoking.


>Keywords: passive smoking; non-smoking partners; cotinine
机译：背景—主要是在与吸烟者结婚的非吸烟者中评估了由被动吸烟引起的肺癌和心脏病的风险，但是如吸入烟量的标记所表明的，对婚姻伴侣暴露程度的定量评估很少。
目标-将英国非吸烟成年人的血浆可替宁浓度与其伴侣的吸烟行为以及人口统计学和其他因素相关。
数据-人口调查。来自英格兰健康调查的两年（1994年和1996年）中的数据。
主要观察指标-与伴侣结婚或同居的非吸烟成年人的血浆可替宁浓度。
结果-非吸烟成年人中可替宁浓度与其伴侣吸烟行为之间的剂量反应关系从非吸烟伴侣的几何平均数为0.31 ng / ml上升至伴侣吸烟30次或更多的人的1.99 ng / ml每天吸烟。此外，秋季，冬季以及处境更不利的人的男性接触率更高，从该国南部到北部的接触率在增加。平均而言，有吸烟伴侣的非吸烟者的可替宁浓度是吸烟者的0.6-0.7％。
结论—如果将可替宁作为风险相关剂量的量度，则隐含的肺癌风险增加与吸烟伙伴一起吸烟的非吸烟者与流行病学研究中观察到的风险一致。伴侣在家中吸烟是非吸烟成年人接触被动吸烟的主要来源。


>关键字：非吸烟伙伴；可替宁

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