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Pros and cons of colonoscopy in management of acute lower gastrointestinal bleeding

机译:结肠镜检查在急性下消化道出血管理中的利弊

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摘要

Acute lower gastrointestinal bleeding (LGIB) is a frequent gastrointestinal cause of hospitalization, particularly in the elderly, and its incidence appears to be on the rise. Endoscopic and radiographic measures are available for the evaluation and treatment of LGIB including flexible sigmoidoscopy, colonoscopy, angiography, radionuclide scintigraphy and multi-detector row computed tomography. Although no modality has emerged as the gold standard in the management of LGIB, colonoscopy is the current preferred initial test for the majority of the patients presenting with hematochezia felt to be from a colon source. Colonoscopy has the ability to diagnose all sources of bleeding from the colon and, unlike the radiologic modalities, does not require active bleeding at the time of the examination. In addition, therapeutic interventions such as cautery and endoclips can be applied to achieve hemostasis and prevent recurrent bleeding. Studies suggest that colonoscopy, particularly when performed early in the hospitalization, can decrease hospital length of stay, rebleeding and the need for surgery. However, results from available small trials are conflicting and larger, multicenter studies are needed. Compared to other management options, colonoscopy is a safe procedure with complications reported in less than 2% of patients, including those undergoing urgent examinations. The requirement of bowel preparation (typically 4 or more liters of polyethylene glycol), the logistical complexity of coordinating after-hours colonoscopy, and the low prevalence of stigmata of hemorrhage complicate the use of colonoscopy for LGIB, particularly in urgent situations. This review discusses the above advantages and disadvantages of colonoscopy in the management of acute lower gastrointestinal bleeding in further detail.
机译:急性下消化道出血(LGIB)是住院的常见胃肠道原因,尤其是在老年人中,其发病率似乎正在上升。内镜和射线照相术可用于LGIB的评估和治疗,包括柔性乙状结肠镜检查,结肠镜检查,血管造影,放射性核素闪烁显像和多排行计算机断层摄影术。尽管在LGIB的治疗中尚无任何方法可以作为金标准,但对于大多数感觉是来自结肠来源的患有便血的患者,结肠镜检查是当前首选的初始检查方法。结肠镜检查具有诊断结肠所有出血源的能力,并且与放射学方式不同,在检查时不需要主动出血。另外,可以应用诸如烧灼和内窥镜之类的治疗性干预措施以止血并防止再次出血。研究表明,结肠镜检查,特别是在住院早期进行时,可以减少住院时间,出血和手术需求。但是,可用的小型试验的结果相互矛盾,因此需要更大的多中心研究。与其他管理方法相比,结肠镜检查是一种安全的方法,据报道并发症的患者不到2%,包括接受紧急检查的患者。肠道准备的要求(通常为4升或更多的聚乙二醇),下班后结肠镜检查协调的后勤复杂性以及出血的柱头感染率低,使LGIB结肠镜检查的使用变得复杂,尤其是在紧急情况下。这篇综述进一步讨论了结肠镜检查在急性下消化道出血处理中的上述优缺点。

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