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首页> 美国卫生研究院文献>World Journal of Oncology >Brain Metastasis From Prostate Adenocarcinoma: Case Report and Review of Literature
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Brain Metastasis From Prostate Adenocarcinoma: Case Report and Review of Literature

机译：前列腺腺癌的脑转移：病例报告和文献复习。

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It is rare for prostate carcinoma to metastasize to the central nervous system. It often represents a terminal event with death in one year frequently due to the advanced systemic disease. Starting by a case report, we also reviewed the relevant literature to focus on this uncommon entity from epidemiology to clinical manifestation and therapeutic strategies. In this article, a case of multiple brain prostate metastasis is reported and a review of relevant literature is also discussed. Treatments available for intracranial metastasis include neurosurgery, external beam radiation and hormonal manipulation. Surgery associated with whole brain radiotherapy seems to be effective in the control of brain lesions both relieving neurological symptoms and prolonging survival, even if prognosis remains dismal. From this case, we concluded that brain metastasis from prostate carcinoma is a rare, terminal event with death in one year frequently due to the advanced systemic disease. A better understanding of the biology of prostate carcinoma will help clarify the basis for its metastasis to the brain.
机译：前列腺癌很少转移到中枢神经系统。它通常代表着一种晚期事件，由于晚期全身性疾病，通常在一年内死亡。从病例报告开始，我们还回顾了相关文献，重点关注从流行病学到临床表现和治疗策略的这一罕见实体。本文报道了多发性脑前列腺转移的病例，并讨论了相关文献。可用于颅内转移的治疗方法包括神经外科手术，外照射和激素操纵。即使预后仍然不佳，与全脑放疗相关的手术似乎在控制脑部病变方面都有效，既缓解了神经系统症状，又延长了生存期。从这个案例中，我们得出结论，由于晚期全身性疾病，前列腺癌的脑转移是罕见的终末事件，一年之内死亡。对前列腺癌生物学的更好理解将有助于阐明其向脑转移的基础。

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