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An Academia-Industry Partnership for Planning and Executing a Community-Based Feeding Study

机译：产学合作计划和执行基于社区的喂养研究

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A research team from Boston Children's Hospital and Harvard Medical School conducted a community-based feeding study in collaboration with Framingham State University (FSU) and Sodexo, the food service contractor at FSU. The study was a randomized controlled trial, implemented on the FSU campus. For the final year of the study, a satellite feeding site was established at Assabet Valley Regional Technical High School. The purpose of the study was to assess the biological effects of different macronutrient diets. An academia-industry partnership was developed to overcome common challenges associated with hospital-based feeding studies. Benefits included the following: a study site outside of Boston (reducing inconvenience for participants), access to a large commercial kitchen and study-specific kiosk (promoting efficiency), collaboration with Sodexo chefs (ensuring palatability of meals), and opportunity to procure food from contracted vendors. The research (academia) and food service (industry) teams worked together to design, plan, and execute intervention protocols using an integrated approach. During execution, the research team was primarily responsible for overseeing treatment fidelity, whereas the food service team provided culinary expertise, with a strong focus on hospitality and food quality. The study was conducted in 3 cohorts between August 2014 and May 2017. Participants received all of their food for ∼30 wk, totaling >160,000 meals. For all 3 cohorts combined, 234 participants provided informed consent, 229 started a standard run-in weight-loss diet, 164 lost a mean ± SD 12% ± 2% of baseline body weight and were randomly assigned to different macronutrient diets for weight-loss maintenance, and 148 completed the study. During the final and largest cohort, as many as 114 participants received daily meals concurrently. The daily cost per participant for preparation and service of weighed meals and snacks was ∼$65. This academia-industry partnership provides a model for controlled feeding protocols in nutrition research, potentially with enhanced cost-effectiveness, practicality, and generalizability. This trial was registered at as .
机译：波士顿儿童医院和哈佛医学院的一个研究小组与弗雷明汉州立大学（FSU）和FSU的食品服务承包商Sodexo合作进行了一项基于社区的喂养研究。该研究是一项在FSU校园实施的随机对照试验。在研究的最后一年，在阿萨贝特谷地区技术高中建立了一个卫星馈电站点。该研究的目的是评估不同常量营养素饮食的生物学效应。建立了学术界和产业界的合作伙伴关系，以克服与基于医院的喂养研究相关的常见挑战。好处包括：在波士顿以外的学习地点（减少参与者的不便），使用大型商业厨房和特定于研究亭的亭子（提高效率），与Sodexo厨师合作（确保饭菜的适口性）以及购买食物的机会签约供应商。研究（学术界）和食品服务（行业）团队通力合作，使用集成方法设计，规划和执行干预方案。在执行过程中，研究团队主要负责监督治疗的保真度，而食品服务团队则提供烹饪方面的专业知识，重点关注酒店和食品质量。该研究在2014年8月至2017年5月之间的3个队列中进行。参与者以大约30周的价格收到了所有食物，总计超过160,000顿饭。对于所有3个队列的总和，有234名参与者提供了知情同意，229名开始了标准的常规减肥饮食，164名失去了基线体重的平均±SD 12％±2％，并被随机分配到不同的常量营养饮食中以减轻体重-损失维护，并且148完成了研究。在最后一个也是最大的队列中，多达114名参与者同时接受了一日三餐。每位参与者准备和提供称量餐点和小吃的每日费用约为65美元。这种学术界与产业界的伙伴关系为营养研究中的可控喂养方案提供了一个模型，可能具有更高的成本效益，实用性和通用性。该审判的注册地址为。

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