• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Computational and Structural Biotechnology Journal >Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships
【2h】

Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public–private partnerships

机译：通过公私伙伴关系促进由微生理系统（组织芯片）计划产生的器官平台的商业化和使用

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Microphysiological systems (organs-on-chips, tissue chips) are devices designed to recapitulate human physiology that could be used to better understand drug responses not easily addressed using other in vivo systems or in vitro animal models. Although still in development, initial results seem promising as tissue chips exhibit in vivo systems-like functional responses. The National Center for Advancing Translation Science (NCATS) identifies this technology as a potential tool that could improve the process of getting safer, more effective treatments to patients, and has led to the Tissue Chip Program, which aims to develop, integrate and validate major organ systems for testing. In addition to organ chip development, NCATS emphasizes disseminating the technology to researchers. Commercialization has become an important issue, reflecting the difficulty of translation from discovery to adoption and wide availability. Therefore, NCATS issued a Request for Information (RFI) targeted to existing partnerships for commercializing tissue chips. The goal was to identify successes, failures and the best practices that could provide useful guidance for future partnerships aiming to make tissue chip technology widely available.
机译：微生理系统（芯片上的器官，组织芯片）是旨在概括人类生理的设备，可用于更好地理解使用其他体内系统或体外动物模型不易解决的药物反应。尽管仍在开发中，但由于组织芯片表现出类似于体内系统的功能反应，因此初步结果似乎很有希望。美国国家翻译科学促进中心（NCATS）将该技术确定为一种潜在工具，可以改善对患者进行更安全，更有效的治疗的过程，并发起了组织芯片计划，该计划旨在开发，整合和验证主要器官系统进行测试。除了器官芯片的开发，NCATS还强调将技术传播给研究人员。商业化已成为一个重要问题，反映了从发现到采用的转换难度以及广泛的可用性。因此，NCATS发布了针对组织纸巾商业化的现有合作伙伴关系的信息请求（RFI）。目的是确定成功，失败和最佳实践，为将来的伙伴关系提供有用的指导，以使组织芯片技术广泛可用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号