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首页> 美国卫生研究院文献>The Journal of Veterinary Medical Science >Relationship between indirect blood pressure and various stages of chronic kidney disease in cats
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Relationship between indirect blood pressure and various stages of chronic kidney disease in cats

机译：猫间接血压与慢性肾脏病各个阶段的关系

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Chronic kidney disease (CKD) is a common cause of secondary systemic hypertension in cats. We investigated the relationship between indirect blood pressure and the prevalence of systemic hypertension in various CKD stages in cats. Client-owned cats (24 control cats and 77 cats with CKD) were included. Biochemical examinations of plasma were conducted by a commercial laboratory. Diseased cats were divided into two groups based on the International Renal Interest Society (IRIS) guidelines (II and III–IV). Indirect blood pressure was measured using an oscillometric technique. Severe hypertension was diagnosed if systolic blood pressure (SBP) was ≥180 mmHg. Indirect blood pressures were significantly higher in IRIS stage III–IV than in the control cats. Of 77 cats with CKD, 25 (32.5%) had severe hypertension. The frequency of severe hypertension increased with an increase in IRIS stage; 0% in the controls, 27.6% in the IRIS stage II, and 47.4% in the IRIS stage III–IV, respectively. The indirect SBP was weakly correlated with urea nitrogen (r=0.27) and creatinine (r=0.23) concentrations in plasma. Binary logistic regression analysis showed that if plasma creatinine concentration is >3.7 mg/dl, cats with CKD had an increased risk for developing severe hypertension (P<0.001). Our results suggest that indirect blood pressure was correlated with the severity of CKD, and the prevalence of severe hypertension increased in cats with severe CKD. The risk of severe hypertension may be high in cats with severe CKD.
机译：慢性肾脏疾病（CKD）是猫继发性系统性高血压的常见原因。我们调查了猫的不同CKD阶段间接血压与全身性高血压患病率之间的关系。客户拥有的猫（24只对照猫和77只CKD猫）包括在内。血浆的生化检查由商业实验室进行。根据国际肾脏兴趣协会（IRIS）指南，患病猫分为两组（II和III–IV）。使用示波法测量间接血压。如果收缩压（SBP）≥180mmHg，则诊断为严重高血压。 IRIS III-IV期的间接血压明显高于对照组。在77例患有CKD的猫中，有25例（32.5％）患有严重的高血压。严重高血压的发生率随着IRIS分期的增加而增加；对照中分别为0％，IIRIS II期为27.6％，IRIS III-IV期为47.4％。间接SBP与血浆中的尿素氮（r = 0.27）和肌酐（r = 0.23）浓度呈弱相关。二元逻辑回归分析表明，如果血浆肌酐浓度> 3.7 mg / dl，患有CKD的猫患严重高血压的风险增加（P <0.001）。我们的结果表明，间接血压与CKD的严重程度相关，并且患有严重CKD的猫的严重高血压患病率增加。患有严重CKD的猫患严重高血压的风险可能很高。

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