Integrated whole-heart computational workflow for inverse potential mapping and personalized simulations

机译：集成的全心计算工作流程可进行逆电位映射和个性化仿真

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摘要

BackgroundIntegration of whole-heart activation simulations and inverse potential mapping (IPM) could benefit the guidance and planning of electrophysiological procedures. Routine clinical application requires a fast and adaptable workflow. These requirements limit clinical translation of existing simulation models. This study proposes a comprehensive finite element model (FEM) based whole-heart computational workflow suitable for IPM and simulations.

机译：背景全心激活模拟和逆电势映射（IPM）的集成可能有益于电生理程序的指导和计划。常规临床应用需要快速且适应性强的工作流程。这些要求限制了现有仿真模型的临床翻译。这项研究提出了一种适用于IPM和仿真的基于综合有限元模型（FEM）的全心计算工作流程。

著录项

期刊名称 Journal of Translational Medicine
作者
P. Bhagirath; A. W. M. van der Graaf; J. de Hooge; N. M. S. de Groot; M. J. W. Götte;
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作者单位

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年(卷),期 2016(14),-1
年度 2016
页码 147
总页数 7
原文格式 PDF
正文语种
中图分类医学史;
关键词
Personalized cardiac model Whole-heart simulation Whole-heart inverse potential mapping FEM based cardiac simulations Patient-specific therapy;

机译：个性化心脏模型;全心模拟;全心逆电位映射;基于FEM的心脏模拟;针对患者的治疗;

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专利

1. Integrated whole-heart computational workflow for inverse potential mapping and personalized simulations [J] . P. Bhagirath, A. W. M. Graaf, J. Hooge, Journal of Translational Medicine . 2016,第1期

机译：集成的全心计算工作流程，可进行逆电位映射和个性化仿真
2. An integrated computational approach of molecular dynamics simulations, receptor binding studies and pharmacophore mapping analysis in search of potent inhibitors against tuberculosis [J] . Agarwal Shivangi, Verma Ekta, Kumar Vivek, Journal of molecular graphics & modelling . 2018,第期

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3. Integrated Computational Tools for Identification of CCR5 Antagonists as Potential HIV-1 Entry Inhibitors: Homology Modeling, Virtual Screening, Molecular Dynamics Simulations and 3D QSAR Analysis [J] . Suri Moonsamy, Radha Charan Dash, Mahmoud E. S. Soliman Molecules . 2014,第4期

机译：用于识别CCR5拮抗剂作为潜在HIV-1进入抑制剂的集成计算工具：同源性建模，虚拟筛选，分子动力学模拟和3D QSAR分析
4. Development of an Integrated Computational Application and Workflow to Assess the Toxicity Potentials of Chemicals [C] . Philip Lee, Feixiong Cheng, Yun Tang, Proceedings of 4th international symposium on pesticides and environmental safety amp; 5th pan Pacific confernce on pesticide science amp; 8th international workshop on crop protection chemistry and regulatory harmonization . 2012

机译：开发综合计算应用程序和工作流程以评估化学品的毒性潜力
5. An Integrated Workflow for Reservoir Modeling and Flow Simulation of the Nikanassin Tight Gas Reservoir in the Western Canada Sedimentary Basin [D] . Deng, Hui 2011

机译：加拿大西部沉积盆地尼卡那辛致密气藏的储层建模和流动模拟的集成工作流
6. Integrated Computational Tools for Identification of CCR5 Antagonists as Potential HIV-1 Entry Inhibitors: Homology Modeling Virtual Screening Molecular Dynamics Simulations and 3D QSAR Analysis [O] . Suri Moonsamy, Radha Charan Dash, Mahmoud E. S. Soliman 2014

机译：用于识别CCR5拮抗剂作为潜在HIV-1进入抑制剂的集成计算工具：同源性建模虚拟筛选分子动力学模拟和3D QSAR分析
7. Integrated whole-heart computational workflow for inverse potential mapping and personalized simulations [O] . 2016

机译：集成的全心计算工作流程，可进行逆电位映射和个性化仿真

Integrated whole-heart computational workflow for inverse potential mapping and personalized simulations

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