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首页> 美国卫生研究院文献>Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders >Effects of Dietary Supplementation with the Solanaceae Plant Alkaloid Anatabine on Joint Pain and Stiffness: Results from an Internet-Based Survey Study
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Effects of Dietary Supplementation with the Solanaceae Plant Alkaloid Anatabine on Joint Pain and Stiffness: Results from an Internet-Based Survey Study

机译：日粮中茄科植物生物碱Anatabine对关节痛和僵硬的影响：基于互联网的调查研究结果

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摘要

Anatabine is a Solanaceae plant family alkaloid marketed in the United States as a dietary supplement. It has demonstrated anti-inflammatory effects in vivo and in vitro, and may be useful for musculoskeletal aches and pains. The purpose of this internet-based survey study was to provide more information about anatabine users who report benefits for joint pain or stiffness. Of the 282 survey respondents, 232 (82%) reported a benefit from anatabine supplementation for one or more joint pain conditions, most commonly the knee, wrists/hands/fingers, shoulder, and back, most often due to osteoarthritis or injury to the joint. Mean scores of joint pain and stiffness were significantly (P < 0.0001) reduced after starting anatabine supplementation, and for most respondents joint pain was virtually eliminated. Around 90% of all individuals rated the effect of anatabine supplementation as good or excellent for joint pain, stiffness, functionality, and overall effects. These results provide evidence that anatabine supplementation can lead to substantial improvement of musculoskeletal aches, pains, and stiffness, and can provide benefits in some individuals for various medical conditions in multiple joint locations.
机译：Anatabine是茄科植物生物碱，在美国作为膳食补充剂销售。它已在体内和体外显示出抗炎作用，可能对肌肉骨骼疼痛和疼痛有用。这项基于互联网的调查研究的目的是提供有关报告了关节痛或僵硬益处的阿那他滨使用者的更多信息。在282位受访者中，有232位（82％）报告说，他汀类药物的补充可以缓解一种或多种关节疼痛，最常见的是膝盖，手腕/手/手指，肩膀和背部，主要是由于骨关节炎或对关节的伤害。联合。开始补充阿他滨后，关节痛和僵硬的平均评分显着降低（P <0.0001），并且对于大多数应答者来说，关节痛实际上得到了消除。大约90％的人认为补充阿那他滨的效果对关节疼痛，僵硬，功能性和整体效果均好或极好。这些结果提供了证据表明，补充Anatabine可以显着改善肌肉骨骼的疼痛，疼痛和僵硬，并且可以在某些个体中为多个关节部位的各种医学状况提供益处。

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