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首页> 美国卫生研究院文献>Clinics in Colon and Rectal Surgery >Anal Intraepithelial Neoplasia and Squamous Cell Cancer of the Anus: So Now My Patient Has Squamous Cell Cancer: Diagnosis Staging and Treatment of Squamous Cell Carcinoma of the Anal Canal and Anal Margin
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Anal Intraepithelial Neoplasia and Squamous Cell Cancer of the Anus: So Now My Patient Has Squamous Cell Cancer: Diagnosis Staging and Treatment of Squamous Cell Carcinoma of the Anal Canal and Anal Margin

机译：肛门上皮内瘤变和肛门鳞状细胞癌：所以现在我的患者患有鳞状细胞癌：肛管和肛缘鳞状细胞癌的诊断分期和治疗

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摘要

Squamous cell carcinomas of the anal canal and the anal margin are rare malignancies that are increasing in incidence. Patients with these tumors often experience delayed treatment due to delay in diagnosis or misdiagnosis of the condition. Distinguishing between anal canal and anal margin tumors has implications for staging and treatment. Chemoradiation therapy is the mainstay of treatment for anal canal squamous cell, with abdominoperineal resection reserved for salvage treatment in cases of persistent or recurrent disease. Early anal margin squamous cell carcinoma can be treated with wide local excision, but more advanced tumors require a combination of chemoradiation therapy and surgical excision.
机译：肛管和肛门边缘的鳞状细胞癌是罕见的恶性肿瘤，其发病率正在增加。患有这些肿瘤的患者通常由于疾病的诊断或误诊延迟而经历延迟治疗。区分肛管和肛缘肿瘤对分期和治疗具有重要意义。化学放射疗法是肛管鳞状细胞治疗的主要手段，对于持续性或复发性疾病，腹部手术切除保留用于抢救治疗。早期的肛门边缘鳞状细胞癌可以通过广泛的局部切除术进行治疗，但更晚期的肿瘤需要化学放疗和手术切除术的结合。

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