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首页> 美国卫生研究院文献>Clinical Cardiology >Primary percutaneous interventions for acute myocardial infarction in octogenarians: A single‐center experience
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Primary percutaneous interventions for acute myocardial infarction in octogenarians: A single‐center experience

机译：高龄人群急性心肌梗死的主要经皮介入治疗：单中心经验

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Background: The majority of cardiovascular deaths occur in the elderly. The safety and results of primary infarct intervention in octogenarians is Not well characterized. Hypothesis: The purpose of this study was to compare the results of primary infarct intervention in octogenarians with those in younger patients during 1997‐1998 and to compare these results to those obtained in octogenarians treated in 1991‐1994. Methods: During 1997‐1998, 40 octogenarians were treated with primary infarct intervention and were compared with 60 randomly selected patients aged < 80 years treated during the same time period. The results in octogenarians were compared with the results in a group of 37 patients of similar age treated in 1991‐1994. The baseline characteristics, procedural results, and hospital outcome were obtained from a prospectively designed interventional database at a busy single‐center program. Results: There was No significant difference in hospital survival between the two groups of patients treated in 1997‐1998 although there was a trend toward higher mortality in the octogenarian group. Length of stay and use of intra‐aortic balloon pumps were greater in the octogenarian group. When the results in octogenarians treated in 1997‐1998 were compared with the group of 37 patients treated in 1991‐1994, the hospital mortality declined from 27 to 10% (p = 0.05). Conclusions: There has been improvement in hospital mortality over the past decade for patients aged ≥ 80 years treated with primary infarct intervention. Hospital resources and length of stay are greater for the octogenarian group. Ongoing research studies are comparing the results of thrombolytic therapy and primary intervention in aged patients.
机译：背景：大多数心血管死亡发生在老年人中。对八十岁以下儿童进行原发性梗塞干预的安全性和结果尚不十分清楚。假设：本研究的目的是比较1997-1998年间八岁老人与较年轻患者的原发性梗塞干预结果，并将这些结果与1991-1994年八岁老人接受的原发梗塞干预结果进行比较。方法：在1997年至1998年期间，对40名八岁老人进行了原发性梗塞治疗，并与同期同期随机选择的60名年龄小于80岁的患者进行了比较。将八岁老人的结果与1991-1994年接受治疗的37名年龄相似的患者进行了比较。基线特征，程序结果和医院结果是从繁忙的单中心计划中的前瞻性设计干预数据库中获得的。结果：尽管在高龄人群中死亡率有增加的趋势，但在1997-1998年期间接受治疗的两组患者的医院生存率没有显着差异。在八十岁以下儿童组中，住院时间和主动脉内球囊泵的使用时间更长。当将1997-1998年接受治疗的八岁老人的结果与1991-1994年接受治疗的37例患者进行比较时，医院死亡率从27％降至10％（p = 0.05）。结论：在过去的十年中，≥80岁的原发性梗塞介入治疗的患者的住院死亡率有所改善。对于八十岁以下儿童，医院资源和住院时间更长。正在进行的研究正在比较老年患者的溶栓治疗和主要干预措施的结果。

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