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Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

机译：使用钙生物传感器表达的斑马鱼纤毛嗅觉神经元检测感觉纤毛病。

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BackgroundPrimary cilia mediate signal transduction by acting as an organizing scaffold for receptors, signalling proteins and ion channels. Ciliated olfactory sensory neurons (OSNs) organize olfactory receptors and ion channels on cilia and generate a calcium influx as a primary signal in odourant detection. In the zebrafish olfactory placode, ciliated OSNs and microvillus OSNs constitute the major OSN cell types with distinct odourant sensitivity.

机译：背景初级纤毛通过充当受体，信号蛋白和离子通道的组织支架来介导信号转导。纤毛嗅觉感觉神经元（OSN）在纤毛上组织嗅觉受体和离子通道，并产生钙流入作为气味检测中的主要信号。在斑马鱼的嗅觉平台中，纤毛OSN和微绒毛OSN构成主要的OSN细胞类型，具有独特的气味敏感性。

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期刊名称 Cilia
作者
Judith G. M. Bergboer; Cameron Wyatt; Christina Austin-Tse; Emre Yaksi; Iain A. Drummond;
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作者单位

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年(卷),期 2018(7),-1
年度 2018
页码 2
总页数 12
原文格式 PDF
正文语种
中图分类
关键词
Cilia Calcium imaging Zebrafish GCaMP5 Olfactory sensory neurons oval/ift88 ift172;

机译：纤毛;钙成像;斑马鱼;GCaMP5;嗅觉神经元;卵形/ ift88;ift172;

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专利

1. Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons [J] . Judith G. M. Bergboer, Cameron Wyatt, Christina Austin-Tse, Cilia . 2018,第1期

机译：使用钙生物传感器表达的斑马鱼纤毛嗅觉神经元检测感觉纤毛病。
2. Concurrent expression of recombination activating genes 1 and 2 in zebrafish olfactory sensory neurons. [J] . Jessen JR, Jessen TN, Vogel SS, Genesis: the journal of genetics and development . 2001,第4期

机译：重组激活基因1和2在斑马鱼嗅觉感觉神经元中的同时表达。
3. Regulation by protein kinase A switching of axonal pathfinding of zebrafish olfactory sensory neurons through the olfactory placode-olfactory bulb boundary. [J] . Yoshida T, Ito A, Matsuda N, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2002,第12期

机译：通过蛋白激酶调节通过嗅斑板-嗅球边界的斑马鱼嗅觉感觉神经元轴突寻路的切换。
4. Application of artificial neural networks on mosquito Olfactory Receptor Neurons for an olfactory biosensor [C] . Bachtiar, Luqman R., Unsworth, Charles P., Newcomb, Richard D. Annual Conference of Japanese Society for Medical and Biological Engineering;Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2013

机译：人工神经网络在嗅觉生物传感器的蚊香嗅觉神经元中的应用
5. Bardet-Biedl syndrome and olfaction: Illuminating cilia and sensory neuron biology in a model of human-ciliopathy [D] . Tadenev, Abigail Lynn Davidson 2011

机译：Bardet-Biedl综合征和嗅觉：启发人纤毛病模型中的纤毛和感觉神经元生物学
6. Patterned Arrangements of Olfactory Receptor Gene Expression in Zebrafish are Established by Radial Movement of Specified Olfactory Sensory Neurons [O] . Xalid Bayramli, Yiğit Kocagöz, Uğurcan Sakizli, -1

机译：斑马鱼的嗅觉受体基因表达的模式安排是通过特定嗅觉感觉神经元的径向运动建立的。
7. Regulation by Protein Kinase A Switching of Axonal Pathfinding of Zebrafish Olfactory Sensory Neurons through the Olfactory Placode–Olfactory Bulb Boundary [O] . Tomoyuki Yoshida, Aya Ito, Naoto Matsuda, 2002

机译：蛋白质激酶调节斑马鱼嗅觉感觉神经元通过嗅觉放置嗅球边界切换锯切嗅觉感觉神经元的切换

Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

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