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Lost in the Mist: Acute Adrenal Crisis Following Intranasal Fluticasone Propionate Overuse

机译:迷雾迷路:鼻内丙酸氟替卡松过量使用后的急性肾上腺危机

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摘要

Introduction. Acute adrenal crisis in relation to nasal steroid overuse has been reported very scantly in English medical literature and remains an underdiagnosed condition. Case presentation. A 55 year-old male presented with altered mental status, retrograde amnesia, fluid refractory hypotension, abdominal pain, fever, and chest pain. Physical examination revealed amnesia, bradypsychia, tachycardia, decreased muscle tone and hyporeflexia. Overuse of nasal steroid was suspected by history. Random early morning cortisol level was < 0.2 mcg/dL. The patient was started on hydrocortisone and within 24 hours he had a full recovery. Conclusion. This one-of-a-kind case describes acute adrenal crisis secondary to withdrawal from inhaled nasal corticosteroids overuse in a patient with particular risk factors. Prevention and early recognition of this disorder can significantly reduce its morbidity and mortality.
机译:介绍。在英国医学文献中,很少有人报道过高的与鼻类固醇过度使用有关的急性肾上腺危机,并且这种病仍未得到充分诊断。案例介绍。一名55岁的男性表现出精神状态改变,逆行性健忘症,难治性低血压,腹痛,发烧和胸痛。体格检查发现失忆,心动过缓,心动过速,肌张力降低和反射不足。历史上怀疑过度使用鼻类固醇激素。清晨随机皮质醇水平<0.2

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