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MicroRNA-365 targets multiple oncogenes to inhibit proliferation invasion and self-renewal of aggressive endometrial cancer cells

机译：MicroRNA-365靶向多种致癌基因以抑制侵袭性子宫内膜癌细胞的增殖侵袭和自我更新

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BackgroundMicroRNA-365 (miR-365) has been reported to be a tumor suppressor miRNA. However, the role of miR-365 in progression of endometrial cancer (EC) has not been explored, in this study, we have found that re-expression of miRNA-365 inhibits cell proliferation, causes apoptosis and senescence.

机译：背景技术据报道，MicroRNA-365（miR-365）是一种抑癌miRNA。但是，尚未探讨miR-365在子宫内膜癌（EC）进程中的作用，在这项研究中，我们发现miRNA-365的重新表达抑制细胞增殖，导致细胞凋亡和衰老。

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期刊名称 Cancer Management and Research
作者
Chunfang Wang; Ke Su; Yanyan Zhang; Weiwei Zhang; Danxia Chu; Qian Zhao; Ruixia Guo;
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作者单位

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年(卷),期 2018(10),-1
年度 2018
页码 5171–5185
总页数 15
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
microRNA-365 endometrial cancer paclitaxel EZH2 FOS;

机译：microRNA-365;子宫内膜癌;紫杉醇;EZH2;FOS;

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专利

1. MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells [J] . Chunfang Wang, Ke Su, Yanyan Zhang, Cancer Management and Research . 2018,第2016期

机译：MicroRNA-365靶向多种致癌基因，以抑制侵袭性子宫内膜癌细胞的增殖，侵袭和自我更新
2. miR-5195-3p Inhibits Proliferation and Invasion of Human Bladder Cancer Cells by Directly Targeting Oncogene KLF5 [J] . Jiang Zhangjie, Zhang Yida, Cao Runfu, Oncology Research . 2017,第7期

机译：miR-5195-3p通过直接靶向癌基因KLF5来抑制人膀胱癌细胞的增殖和侵袭
3. MicroRNA-218 inhibits glioma invasion, migration, proliferation, and Cancer stem-like cell self-renewal by targeting the polycomb group gene Bmi1 [J] . TuY., GaoX., LiG., Cancer research: The official organ of the American Association for Cancer Research, Inc . 2013,第19期

机译：MicroRNA-218通过靶向多梳子基团基因Bmi1抑制神经胶质瘤的侵袭，迁移，增殖和癌干样细胞的自我更新
4. Effect of Hepatocyte Growth Factor on the Expression of Matrix Metalloproteinases in the Invasion of Endometrial Cancer Cells in a Three-Dimensional Coculture System [C] . Hee-Sug Ryu, Dong-Soon Choi, Ki-Hong Chang, International Symposium on the Cell and Molecular Biology of Endometrial Carcinoma . 2003

机译：肝细胞生长因子对三维共培养系统中子宫内膜癌细胞侵袭中基质金属蛋白酶表达的影响
5. Dual strands of the miR-223 duplex (miR-223-5p and miR-223-3p) inhibit cancer cell aggressiveness : targeted genes are involved in bladder cancer pathogenesis [D] . SUGAWARA, Sho 2019

机译：miR-223双链体的双链（miR-223-5p和miR-223-3p）抑制癌细胞侵袭性：靶向基因参与膀胱癌的发病机理
6. MicroRNA-101 targets EZH2 MCL-1 and FOS to suppress proliferation invasion and stem cell-like phenotype of aggressive endometrial cancer cells [O] . Yosuke Konno, Peixin Dong, Ying Xiong, 2014

机译：MicroRNA-101靶向EZH2MCL-1和FOS以抑制侵袭性子宫内膜癌细胞的增殖侵袭和干细胞样表型
7. MicroRNA-365 targets multiple oncogenes to inhibit proliferation, invasion, and self-renewal of aggressive endometrial cancer cells [O] . Chunfang Wang, Ke Su, Yanyan Zhang, 2018

机译：microRNA-365靶向多种癌变，以抑制侵袭性子宫内膜癌细胞的增殖，侵袭和自我更新

MicroRNA-365 targets multiple oncogenes to inhibit proliferation invasion and self-renewal of aggressive endometrial cancer cells

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