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首页> 美国卫生研究院文献>BMC Veterinary Research >Development of intestinal microflora and occurrence of diarrhoea in sucking foals: effects of Bacillus cereus var. toyoi supplementation
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Development of intestinal microflora and occurrence of diarrhoea in sucking foals: effects of Bacillus cereus var. toyoi supplementation

机译：吮吸小马驹肠道菌群的发育和腹泻的发生：蜡状芽孢杆菌的作用。丰井补品

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BackgroundAlmost all foals develop transient diarrhoea within the first weeks of life. Studies indicated different viral, bacterial, and parasitic causes, such as rotavirus, Clostridium perfringens, Escherichia coli, and Cryptosporidium are discussed. But little is known about the development of intestinal microflora in foals. The present study investigated whether the supplementation with Bacillus cereus var. toyoi would modify the developing intestinal microflora and consequently reduce diarrhoea in foals. From birth, the foals were randomly assigned to three treatment groups: placebo (10 mL isotonic NaCl, n = 8), low dosage (LD; 5 × 108 cfu B. cereus var. toyoi, n = 7) and high dosage (HD; 2 × 109 cfu B. cereus var. toyoi, n = 10). Treatment groups were supplemented orally once a day for 58 days. Faeces scoring and sampling were performed within the first 24 h after birth and on day 9, 16, 23, 30, 44, 58 of the foal’s life and also on the first day of diarrhoea. Culture-plate methods were used to analyse the bacterial microflora.
机译：背景几乎所有小马驹在生命的最初几周内都会出现暂时性腹泻。研究表明，讨论了不同的病毒，细菌和寄生虫病原，例如轮状病毒，产气荚膜梭状芽胞杆菌，大肠杆菌和隐孢子虫。但是对小肠中肠道菌群的发育了解甚少。本研究调查是否补充蜡状芽孢杆菌。丰井将改变发育中的肠道菌群，从而减少小马驹的腹泻。从出生起，将小马驹随机分为三个治疗组：安慰剂（10 mL等渗NaCl，n = 8），低剂量（LD; 5×10 8 cfu B. cereus var.toyoi，n = 7）和高剂量（HD; 2×10 9 cfu B. cereus var.toyoi，n = 10）。治疗组每天口服58天。在出生后的头24小时内，小马生命的第9、16、23、30、44、58天以及腹泻的第一天进行粪便评分和采样。培养板法用于分析细菌菌群。

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