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Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

机译：DNA依赖的RNA聚合酶和真核RNA依赖的RNA聚合酶的催化亚基之间的进化联系和RNA聚合酶的起源

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BackgroundThe eukaryotic RNA-dependent RNA polymerase (RDRP) is involved in the amplification of regulatory microRNAs during post-transcriptional gene silencing. This enzyme is highly conserved in most eukaryotes but is missing in archaea and bacteria. No evolutionary relationship between RDRP and other polymerases has been reported so far, hence the origin of this eukaryote-specific polymerase remains a mystery.

机译：背景真核RNA依赖性RNA聚合酶（RDRP）参与转录后基因沉默过程中调控microRNA的扩增。该酶在大多数真核生物中高度保守，但在古细菌和细菌中却缺失。到目前为止，尚无RDRP与其他聚合酶之间进化关系的报道，因此，这种真核生物特异性聚合酶的起源仍是一个谜。

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期刊名称 BMC Structural Biology
作者
Lakshminarayan M Iyer; Eugene V Koonin; L Aravind;
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作者单位

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年(卷),期 2003(3),-1
年度 2003
页码 1
总页数 23
原文格式 PDF
正文语种
中图分类生物物理学;
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入库时间 2022-08-17 14:02:45

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1. Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases [J] . Lakshminarayan M Iyer, Eugene V Koonin, L Aravind BMC Structural Biology . 2003,第1期

机译：DNA依赖的RNA聚合酶和真核RNA依赖的RNA聚合酶的催化亚基之间的进化联系和RNA聚合酶的起源
2. Bacterial RNA polymerase subunit ω and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly [J] . Leonid Minakhin, Sechal Bhagat, Adrian Brunning Proceedings of the National Academy of Sciences of the United States of America . 2001,第3期

机译：细菌RNA聚合酶亚基ω和真核RNA聚合酶RPB6是序列，结构和功能同源物，可促进RNA聚合酶装配
3. Identification of an ortholog of the eukaryotic RNA polymerase III subunit RPC34 in Crenarchaeota and Thaumarchaeota suggests specialization of RNA polymerases for coding and non-coding RNAs in Archaea [J] . Fabian Blombach, Kira S Makarova, Jeannette Marrero, Biology Direct . 2009,第1期

机译：Crenarchaeota和Thaumarchaeota中真核RNA聚合酶III亚单位RPC34直系同源物的鉴定表明，RNA聚合酶专门用于古细菌中的编码和非编码RNA。
4. Bioinformatics Analysis of Mutant Structure and Functional Sites of Foot-and-Mouth Disease virus RNA-dependent RNA polymerase [C] . Tao Zeng, Zhongxi Mo 第二届生物计算：理论及应用国际会议（The Second International Confere . 2007

机译：口蹄疫病毒RNA依赖性RNA聚合酶突变结构和功能位点的生物信息学分析
5. Subunit compositions of Arabidopsis DNA-dependent RNA polymerases and the roles of the plant-specific RNA polymerases IV and V in gene silencing. [D] . Ream, Thomas Scott. 2009

机译：拟南芥DNA依赖性RNA聚合酶的亚基组成以及植物特异性RNA聚合酶IV和V在基因沉默中的作用。
6. Characterization of a 7-kilodalton subunit of vaccinia virus DNA-dependent RNA polymerase with structural similarities to the smallest subunit of eukaryotic RNA polymerase II. [O] . B Y Amegadzie, B Y Ahn, B Moss 1992

机译：牛痘病毒DNA依赖性RNA聚合酶的7-千达尔顿亚基的表征其结构与真核RNA聚合酶II的最小亚基相似。
7. Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases [O] . Iyer Lakshminarayan M, Koonin Eugene V, Aravind L 2003

机译：DNA依赖的RNA聚合酶和真核RNA依赖的RNA聚合酶的催化亚基之间的进化联系和RNA聚合酶的起源

Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

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