首页> 美国卫生研究院文献>BMC Dermatology >Mapping randomized controlled trials of treatments for eczema - The GREAT database (The Global Resource of Eczema Trials: a collection of key data on randomized controlled trials of treatments for eczema from 2000 to 2010)
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Mapping randomized controlled trials of treatments for eczema - The GREAT database (The Global Resource of Eczema Trials: a collection of key data on randomized controlled trials of treatments for eczema from 2000 to 2010)

机译:绘制湿疹治疗的随机对照试验图-GREAT数据库(全球湿疹试验资源:2000年至2010年治疗湿疹的随机对照试验关键数据的集合)

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摘要

BackgroundMassive duplication of effort occurs when researchers all over the world undertake extensive searches for randomized controlled trials when preparing systematic reviews, when developing evidence-based guidelines and when applying for research funding for eczema treatments. Such duplication wastes valuable resources.Searching for randomized controlled trials of eczema is a laborious task involving scrutiny of thousands of individual references from diverse electronic databases in order to obtain a few papers of interest. Clinicians and patients who wish to find out more about a particular treatment are at risk of missing the relevant evidence if they are not trained in electronic bibliographic searching. Systematic reviews cannot be relied upon to comprehensively inform current optimal eczema treatments due to incomplete coverage and because many may be out of date.An international, publically available and comprehensive resource which brings together all randomized controlled trials on eczema treatment using a highly sensitive search has the potential to release more filtered knowledge about patient care to those who need it most and to significantly shorten the duration and costs of many clinical eczema research and guideline projects.
机译:背景技术当全世界的研究人员在准备系统评价,制定循证指南以及为湿疹治疗申请研究经费时,对随机对照试验进行广泛搜索时,就会发生大量重复工作。这样的重复浪费了宝贵的资源。寻找湿疹的随机对照试验是一项艰巨的任务,涉及对来自不同电子数据库的成千上万的个人参考文献进行仔细检查,以获取感兴趣的论文。如果临床医生和患者未接受电子书目搜索方面的培训,则有可能错过相关证据的风险。由于覆盖范围不完全以及许多可能已过时,因此不能依靠系统的综述来全面了解当前的最佳湿疹治疗方法。国际上可公开获得的综合资源使用高度敏感的搜索将湿疹治疗的所有随机对照试验汇总在一起,有可能向最需要的人发布更多有关患者护理的过滤知识,并显着缩短许多临床湿疹研究和指南项目的时间和成本。

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