• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>BMC Immunology >Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective observational study
【2h】

Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective observational study

机译：回顾白细胞计数：未成熟的粒细胞计数作为区分SIRS和败血症的诊断标志物-前瞻性观察研究

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BackgroundSepsis is a serious disease condition and a major cause of intensive care unit (ICU) admission. Its diagnosis in critically ill patients is complicated. To diagnose an infection rapidly, and to accurately differentiate systemic inflammatory response syndrome (SIRS) from sepsis, is challenging yet early diagnosis is vital for early induction of an appropriate therapy. The aim of this study was to evaluate whether the immature granulocyte (IG) count is a useful early diagnostic marker of sepsis compared to other markers. Therefore, a total of 70 consecutive surgical intensive care patients were assessed. IGs were measured from whole blood samples using an automated analyzer. C-reactive protein (CRP), lipopolysaccharide binding protein (LBP) and interleukin-6 (IL-6) concentrations were also determined. The observation period was a maximum of 21 days and ended with the patients’ discharge from ICU or death. Receiver operating characteristic (ROC) analyses were conducted and area under the curve (AUC) was calculated to determine sensitivities and specificities for the parameters.
机译：背景脓毒症是一种严重的疾病，是重症监护病房（ICU）入院的主要原因。它在重症患者中的诊断很复杂。快速诊断感染并准确区分系统性炎症反应综合征（SIRS）与脓毒症是一项艰巨的任务，但早期诊断对于早期诱导合适的治疗至关重要。这项研究的目的是评估与其他标记相比，未成熟粒细胞（IG）计数是否是败血症的有用早期诊断标记。因此，总共评估了70名连续外科重症监护患者。使用自动分析仪从全血样本中测量IG。还测定了C反应蛋白（CRP），脂多糖结合蛋白（LBP）和白介素6（IL-6）的浓度。观察期最长为21天，以患者从ICU出院或死亡告终。进行接收器工作特性（ROC）分析，并计算曲线下面积（AUC），以确定参数的敏感性和特异性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号