首页> 美国卫生研究院文献>BMC Genomics >CNVs into the wild: screening the genomes of conifer trees (Picea spp.) reveals fewer gene copy number variations in hybrids and links to adaptation

【2h】

CNVs into the wild: screening the genomes of conifer trees (Picea spp.) reveals fewer gene copy number variations in hybrids and links to adaptation

机译：CNV进入野外：对针叶树（Picea spp。）的基因组进行筛选后发现杂种中较少的基因拷贝数变异并且与适应相关

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundCopy number variations (CNVs) have been linked to different phenotypes in human, including many diseases. A genome-scale understanding of CNVs is available in a few plants but none are wild species, leaving a knowledge gap regarding their genome biology and evolutionary role. We developed a reliable CNV detection method for species lacking contiguous reference genome. We selected multiple probes within 14,078 gene sequences and developed comparative genome hybridization on arrays. Gene CNVs were assessed in three full-sib families from species with 20 Gb genomes, i.e., white and black spruce, and interior spruce - a natural hybrid.

机译：背景拷贝数变异（CNV）已与人类的不同表型相关联，包括许多疾病。在少数植物中可获得对CNV的基因组规模的了解，但都不是野生物种，因此在有关其基因组生物学和进化作用方面存在知识空白。我们为缺少连续参考基因组的物种开发了一种可靠的CNV检测方法。我们在14,078个基因序列中选择了多个探针，并在阵列上开发了比较基因组杂交。在具有20 Gb基因组的物种的三个全同胞家族中评估了基因CNV，即白云杉和黑云杉以及内部云杉-自然杂种。

著录项

期刊名称 BMC Genomics
作者
Julien Prunier; Sébastien Caron; John MacKay;
展开▼
作者单位

展开▼
年(卷),期 2017(18),-1
年度 2017
页码 97
总页数 12
原文格式 PDF
正文语种
中图分类遗传学;应用微生物学;
关键词
Copy number variation Comparative genomic hybridization Non-model species Genomic structural variation Genome architecture Species hybridization Picea glauca Picea mariana Picea Engelmanni conifers;

机译：拷贝数变异;比较基因组杂交;非模型物种;基因组结构变异;基因组结构;物种杂交;青云杉;云杉云杉;云杉Engelmanni;针叶树;

相似文献

外文文献
中文文献
专利

1. CNVs into the wild: screening the genomes of conifer trees ( Picea spp. ) reveals fewer gene copy number variations in hybrids and links to adaptation [J] . Julien Prunier, Sébastien Caron, John MacKay BMC Genomics . 2017,第1期

机译：CNV进入野外：筛选针叶树（Picea spp。）的基因组可以发现杂种中较少的基因拷贝数变异，并且可以适应
2. CNVs into the wild: screening the genomes of conifer trees ( Picea spp. ) reveals fewer gene copy number variations in hybrids and links to adaptation [J] . Julien Prunier, Sébastien Caron, John MacKay BMC Genomics . 2017,第1期

机译：CNV进入野外：筛选针叶树（Picea spp。）的基因组可以发现杂种中较少的基因拷贝数变异，并且可以适应
3. Genome-wide Association Study (GWAS) of Germline Copy Number Variations (CNVs) Reveal Genetic Risks of Prostate Cancer in Chinese population [J] . Yishuo Wu, Haitao Chen, Guangliang Jiang, Journal of Cancer . 2018,第5期

机译：生殖细胞拷贝数变异（CNV）的全基因组关联研究（GWAS）揭示了中国人群前列腺癌的遗传风险
4. Classification of genome-wide copy number variations and their associated SNP and gene networks analysis [C] . 2010 IEEE International Conference on Bioinformatics and Biomedicine . 2010

机译：全基因组拷贝数变异的分类及其相关的SNP和基因网络分析
5. An Integrative Approach to Linking Genes, Brain, and Behavior in 22q11.2 Copy Number Variations [D] . Lin, Amy. 2021

机译：将基因，大脑和行为联系在22Q11.2中的综合方法
6. Targeted isolation sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome [O] . Björn Hamberger, Dawn Hall, Mack Yuen, 2009

机译：针叶树防御中涉及的萜类合酶和细胞色素P450基因的两个白云杉（Picea glauca）BAC克隆的靶向分离序列装配和表征揭示了针叶树基因组的见解
7. CNVs into the wild: screening the genomes of conifer trees () reveals fewer gene copy number variations in hybrids and links to adaptation [O] . 2017

机译：CNV进入野外：对针叶树的基因组进行筛选（）可以发现杂种中较少的基因拷贝数变异，并且可以适应

CNVs into the wild: screening the genomes of conifer trees (Picea spp.) reveals fewer gene copy number variations in hybrids and links to adaptation

摘要

著录项

相似文献

相关主题

期刊订阅