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Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine

机译：荧光胺预柱衍生后通过非萃取高效液相色谱-荧光检测法测定血浆中来那度胺的含量

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摘要

BackgroundLenalidomide (LND) is a new potent drug used for treatment of multiple myeloma. For its pharmacokinetic studies and therapeutic monitoring, a proper analytical method was required.

机译：背景来那度胺（LND）是一种用于治疗多发性骨髓瘤的新型有效药物。对于其药代动力学研究和治疗监测，需要一种适当的分析方法。

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期刊名称 BMC Chemistry
作者
Nasr Y Khalil; Ibrahim A Darwish; Tanveer A Wani; Abdel-Rahman A Al-Majed;
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作者单位

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年(卷),期 2013(7),-1
年度 2013
页码 52
总页数 7
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
Lenalidomide Fluorescamine HPLC Fluorescence detection Therapeutic drug Monitoring Pharmacokinetic studies;

机译：来那度胺;氟胺;HPLC;荧光检测;治疗药物;监测;药代动力学研究;

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专利

1. Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine [J] . Nasr Y Khalil, Ibrahim A Darwish, Tanveer A Wani, Chemistry central journal . 2013,第1期

机译：荧光胺预柱衍生后，通过非萃取高效液相色谱-荧光检测法测定血浆中来那度胺的含量
2. Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine [J] . Nasr Y Khalil, Ibrahim A Darwish, Tanveer A Wani, Chemistry central journal . 2013,第1期

机译：荧光胺预柱衍生后，通过非萃取高效液相色谱-荧光检测法测定血浆中来那度胺的含量
3. Simple determination of L-hydroxyproline in idiopathic pulmonary fibrosis lung tissues of rats using non-extractive high-performance liquid chromatography coupled with fluorescence detection after pre-column derivatization with novel synthetic 9-acetylimidazol-carbazole [J] . Ren Yan, Zhao Juanjuan, Shi Yanan, Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis . 2017,第期

机译：用非引诱式高效液相色谱法耦合荧光检测与新型合成9-乙酰咪唑 - 咔唑，用非引诱式高效液相色谱法测定大鼠特发性肺纤维化肺组织L-羟脯氨酸大鼠肺纤维化肺组织
4. Pre-column Derivatization RP-HPLC Determination of Amino Acids in Asparagi Radix before and after Heating Process [C] . Zhihong Shi, Hui Li, Zhimin Li International Conference on Agricultural and Natural Resources Engineering . 2014

机译：柱前衍生化RP-HPLC在加热过程前后芦笋基氨酸中氨基酸的测定
5. A non-derivatization approach to HPLC fluorescence detection for some important amino group-containing compounds based on a ligand displacement reaction. [D] . Yang, Min. 2000

机译：基于配体置换反应的一些重要的含氨基化合物的HPLC荧光检测的非衍生化方法。
6. A rapid method for the determination of dopamine in porcine muscle by pre-column derivatization and HPLC with fluorescence detection [O] . Hong-Xia Zhao, Hui Mu, Yan-Hong Bai, 2011

机译：柱前衍生-高效液相色谱-荧光检测法快速测定猪肌肉中多巴胺
7. Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine [O] . Nasr Y Khalil, Ibrahim A Darwish, Tanveer A Wani, 2013

机译：荧光胺预柱衍生后，通过非萃取高效液相色谱-荧光检测法测定血浆中来那度胺的含量

Trace determination of lenalidomide in plasma by non-extractive HPLC procedures with fluorescence detection after pre-column derivatization with fluorescamine

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