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LEAping to conclusions: A computational reanalysis of late embryogenesis abundant proteins and their possible roles

机译:总结:晚期胚胎发生丰富蛋白的计算重新分析及其可能的作用

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摘要

BackgroundThe late embryogenesis abundant (LEA) proteins cover a number of loosely related groups of proteins, originally found in plants but now being found in non-plant species. Their precise function is unknown, though considerable evidence suggests that LEA proteins are involved in desiccation resistance. Using a number of statistically-based bioinformatics tools the classification of a large set of LEA proteins, covering all Groups, is reexamined together with some previous findings. Searches based on peptide composition return proteins with similar composition to different LEA Groups; keyword clustering is then applied to reveal keywords and phrases suggestive of the Groups' properties.
机译:背景晚期胚胎发生丰富(LEA)蛋白覆盖了许多松散相关的蛋白质组,这些蛋白质最初在植物中发现,但现在在非植物物种中发现。尽管大量证据表明LEA蛋白与抗干燥性有关,但其确切功能尚不清楚。使用许多基于统计学的生物信息学工具,对涵盖所有组的大量LEA蛋白质的分类以及一些先前的发现进行了重新检查。基于肽组成的搜索将组成相似的蛋白质返回给不同的LEA组;然后应用关键字聚类来揭示暗示组属性的关键字和短语。

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