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Light scattering from edematous human corneal grafts’ microstructure: experimental study and electromagnetic modelization

机译:水肿性人类角膜移植物微结构的光散射:实验研究和电磁建模

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摘要

Along with the lens, the cornea is the only transparent tissue in the human body. However, the development of an edema involves structural disturbances increasing light scattering and leading to the opacification of the cornea. Several mechanisms of transparency loss have been studied in the literature, but the whole phenomenon is complex and the part played by each scatterer is still unclear. We propose here to study human corneal grafts combining microscopic OCT imagery with far-field measurement of the scattered light in the reflected half-space. We introduce afterwards numerical calculations based on electromagnetic equations solved with first order approximation to link the observed microscopic-scale structural modifications with the intensity level of the scattered light, and to try and quantify the relationship between them.
机译:与晶状体一起,角膜是人体中唯一的透明组织。然而,水肿的发展涉及结构性扰动,增加了光散射并导致角膜混浊。文献中已经研究了几种透明度损失的机理,但是整个现象很复杂,每个散射体所起的作用仍然不清楚。我们在这里建议结合显微镜OCT图像和反射半空间中散射光的远场测量来研究人类角膜移植物。随后,我们将基于基于电磁方程的一阶近似解进行数值计算,以将观察到的微观结构变化与散射光的强度水平联系起来,并试图量化它们之间的关系。

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