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Electrochemical study and application on rutin at chitosan/graphene films modified glassy carbon electrode

机译:芦丁在壳聚糖/石墨烯薄膜修饰玻碳电极上的电化学研究及应用

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摘要

Graphene (G) was dispersed into 0.5% chitosan (Chit) solution, then the composite films were coated on glassy carbon electrode (GCE), the electrochemical behavior of rutin on a Chit/G modified GCE was investigated and the electrochemical parameters of rutin were calculated. Rutin effectively accumulated on the Chit/G/GCE and caused a pair of redox peaks at around 408 mV and 482 mV (vs. SCE) in 0.1 M phosphate buffer solution (pH 4.0). Under optimized conditions, the anodic peak current was linear to the rutin concentration in the range of 5×10−7–1.04×10−5 M. The regression equation was: y=9.9219x–0.0025, r= 0.9958. The proposed method was successfully used for the determination of rutin content in tablet samples with satisfactory results.
机译:将石墨烯(G)分散在0.5%的壳聚糖(Chit)溶液中,然后将复合膜涂覆在玻璃碳电极(GCE)上,研究芦丁在Chit / G修饰GCE上的电化学行为,并测定芦丁的电化学参数计算。芦丁有效积聚在Chit / G / GCE上,并在0.1M磷酸盐缓冲溶液(pH 4.0)中在408mV和482mV(vs.SCE)处产生一对氧化还原峰。在优化条件下,阳极峰值电流与芦丁浓度呈线性关系,范围为5×10 −7 –1.04×10 −5 M。回归方程为: y = 9.9219x–0.0025,r = 0.9958。该方法成功用于片剂中芦丁含量的测定,结果令人满意。

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