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Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

机译：选择性繁育的新奇表型对雄性和雌性大鼠服用可卡因的动机的影响

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BackgroundGender and enhanced novelty reactivity can predispose certain individuals to drug abuse. Previous research in male and female rats selectively bred for high or low locomotor reactivity to novelty found that bred High Responders (bHRs) acquire cocaine self-administration more rapidly than bred Low Responders (bLRs) and that bHR females in particular self-administered more cocaine than the other groups. The experiments presented here aimed to determine whether an individual's sex and behavioral phenotype interact to affect motivation to take cocaine.

机译：背景性别和新颖性增强的反应性可能使某些人容易滥用药物。先前在雄性和雌性大鼠中选择性繁殖出对新奇的高或低运动反应性的研究发现，繁殖出的高响应者（bHR）比繁殖出的低响应者（bLRs）更快获得可卡因自我给药，特别是雌性bHR尤其是自我给药更多的可卡因比其他群体。这里提出的实验旨在确定一个人的性别和行为表型是否相互作用，从而影响服用可卡因的动机。

著录项

期刊名称 Biology of Sex Differences
作者
Jennifer A Cummings; Brooke A Gowl; Christel Westenbroek; Sarah M Clinton; Huda Akil; Jill B Becker;
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年(卷),期 2011(2),-1
年度 2011
页码 3
总页数 10
原文格式 PDF
正文语种
中图分类生物学;
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1. Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats [J] . Jennifer A Cummings, Brooke A Gowl, Christel Westenbroek, Biology of Sex Differences . 2011,第1期

机译：选择性繁育的寻求新奇表型对雄性和雌性大鼠服用可卡因的动机的影响
2. The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively bred High-Responder and Low-Responder rats. [J] . Davis BA, Clinton SM, Akil H, Pharmacology, Biochemistry and Behavior . 2008,第3期

机译：寻求新奇表型和性别差异对选择性饲养高响应者和低响应者大鼠可卡因自我给药获得的影响。
3. Impulsivity on a Go/No-go task for intravenous cocaine or food in male and female rats selectively bred for high and low saccharin intake. [J] . Anker JJ, Gliddon LA, Carroll ME Behavioural pharmacology . 2008,第5a6期

机译：对雄性和雌性大鼠静脉内注射可卡因或食物进行有/无用任务时的冲动性，可以选择高和低糖精摄入。
4. Evolution of attitudes and motivations of male and female students towards physics and its learning at both high school and engineering university degrees [C] . ENDIKA ARANDIA, KRISTINA ZUZA, JENARO GUISASOLA International Conference on Engineering Education . 2015

机译：高中和工程大学学学生雄性和女性学生态度与动机的演变及其学习
5. The effects of stress on spatial acquisition and performance in rats selectively bred for the tendency to stress eat or non-eat. [D] . Brewster, Keith Z. 2010

机译：应激对大鼠空间获取和运动能力的影响有选择地繁殖，使其具有应激性进食或不进食的趋势。
6. The effects of novelty-seeking phenotypes and sex differences on acquisition of cocaine self-administration in selectively-bred High-Responder and Low-Responder rats [O] . Brooke A. Davis, Sarah M. Clinton, Huda Akil, -1

机译：寻求新奇表型和性别差异对选择性饲养高响应者和低响应者大鼠可卡因自我给药获得的影响
7. Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats [O] . Cummings, Jennifer A, Gowl, Brooke A, Westenbroek, Christel, 2015

机译：选择性繁殖寻求新型表型对雄性和雌性大鼠服用可卡因动机的影响

Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

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