Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila

机译：嗜油线虫（Xenorhabdus nematophila）抗葡萄球菌天然产物线虫素的合成与合成孔径雷达（SAR）

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

The repeated and improper use of antibiotics had led to an increased number of multiresistant bacteria. Therefore, new lead structures are needed. Here, the synthesis and an expanded structure–activity relationship of the simple and antistaphylococcal amide nematophin from Xenorhabdus nematophila and synthetic derivatives are described. Moreover, the synthesis of intrinsic fluorescent derivatives, incorporating azaindole moieties was achieved for the first time.

机译：抗生素的反复和不当使用导致多重耐药菌数量增加。因此，需要新的引线结构。在这里，描述了来自嗜血线虫（Xenorhabdus nematophila）和合成衍生物的简单和抗葡萄球菌酰胺线虫素的合成及其扩展的构效关系。此外，首次实现了合成具有氮杂吲哚部分的内在荧光衍生物的合成。

著录项

期刊名称 Beilstein Journal of Organic Chemistry
作者
Frank Wesche; Hélène Adihou; Thomas A Wichelhaus; Helge B Bode;
展开▼
作者单位

展开▼
年(卷),期 2019(15),-1
年度 2019
页码 535–541
总页数 7
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
azaindole fluorescent dye MRSA nematophin Staphylococcus aureus;

机译：印za吲哚;荧光染料;MRSA;线虫素;金黄色葡萄球菌;

相似文献

外文文献
中文文献
专利

1. Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila [J] . Frank Wesche, Hélène Adihou, Thomas A. Wichelhaus, Beilstein journal of organic chemistry. . 2019,第1期

机译：嗜油线虫（Xenorhabdus nematophila）抗葡萄球菌天然产物线虫素的合成和SAR
2. New Applications of PhI(OAc)2 in Synthesis: Total Synthesis and SAR Development of Potent Antitumor Natural Product Psymberin/Irciniastatin A [J] . Ning Shao, Xianhai Huang, Anandan Palani, Synthesis: International Journal of Methods in Synthetic Organic Chemistry . 2009,第17期

机译：PhI（OAc）2在合成中的新应用：有效的抗肿瘤天然产物Psymberin / Irciniastatin A的全合成和SAR开发
3. New Applications of PhI(OAc)2 in Synthesis: Total Synthesis and SAR Development of Potent Antitumor Natural Product Psymberin/Irciniastatin A [J] . Ning Shao, Xianhai Huang, Anandan Palani, Synthesis: International Journal of Methods in Synthetic Organic Chemistry . 2009,第17期

机译：PHI（OAC）2在合成中的新应用：有效抗肿瘤天然产物PSYMBERIN / IRCINIASTATIN A的总合成和SAR发育
4. Purification and comparison of anti-feeding proteins between extracellular and intracellular protein of Xenorhabdus nematophila var. Pekingensis [C] . X F Yang, B J Yang, H W Yang, International Plant Protection Congress . 2007

机译：Xenorhabdus nematophila VAR细胞外和细胞内蛋白质抗饲喂蛋白的纯化和比较。 Pekingensis.
5. A De Novo Approach Towards Glycosylation using Iterative Pd-/B-Dual Catalysis: Applications in Natural Products Synthesis, Digitoxin analogues, Oligomannose motifs and their SAR Studies. [D] . Bajaj, Sumit O. 2015

机译：从头开始使用迭代Pd- / B-双重催化进行糖基化的方法：在天然产物合成，数字毒素类似物，寡甘露糖基序及其SAR研究中的应用。
6. LuxS-dependent AI-2 production is not involved in global regulation of natural product biosynthesis in Photorhabdus and Xenorhabdus [O] . Antje K. Heinrich, Merle Hirschmann, Nick Neubacher, -1

机译：依赖LuxS的AI-2生产不参与Photorhabdus和Xenorhabdus天然产物生物合成的全球调控
7. Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila [O] . Frank Wesche, Hélène Adihou, Thomas A Wichelhaus, 2019

机译：来自Xenorhabdus nematophila的抗视性天然产物Nematophin的合成和SAR

Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila

摘要

著录项

相似文献

相关主题

期刊订阅