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首页> 美国卫生研究院文献>Journal of Pediatric Intensive Care >Continuous octreotide infusion for treatment of upper gastrointestinal bleeding due to portal hypertension in children: An observational study from pediatric intensive care unit
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Continuous octreotide infusion for treatment of upper gastrointestinal bleeding due to portal hypertension in children: An observational study from pediatric intensive care unit

机译：连续奥曲肽输注治疗小儿门静脉高压症上消化道出血：小儿重症监护室的观察性研究

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Evaluate the usage of octreotide for the control of acute upper gastrointestinal bleeding in children with portal hypertension. A retrospective electronic database analysis of these children was performed over a period of five years. Setting was a tertiary pediatric intensive care. Case notes of 18 encounters in 13 children were reviewed. A loading dose (1.27 ± 0.76 µg/kg) was administered in seven, with median starting dose of 1.44 ± 1.19 µg/kg/h in all other episodes. The mean maximum dose was 1.68 ± 1.38 µg/kg/h. Re-bleeding occurred in one third; hemostasis was eventually achieved in all. Octreotide infusion appears to be safe and effective in controlling pediatric upper gastrointestinal bleeding due to portal hypertension. We also recommend its use in community and rural hospital settings prior to transfer of such patients to a tertiary care center.
机译：评估奥曲肽在控制门静脉高压患儿急性上消化道出血中的应用。对这些儿童进行了为期五年的回顾性电子数据库分析。设置是三级儿科重症监护室。回顾了13名儿童中18次遭遇的病例记录。七次服用负荷剂量（1.27±0.76 µg / kg），其他所有发作的中位起始剂量为1.44±1.19 µg / kg / h。平均最大剂量为1.68±1.38 µg / kg / h。三分之一发生再出血；最终全部实现了止血。奥曲肽输注在控制门静脉高压引起的小儿上消化道出血方面似乎是安全有效的。我们还建议在将此类患者转移到三级护理中心之前，先在社区和乡村医院中使用它。

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