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首页> 美国卫生研究院文献>Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology >Effect of condensed tannins supplementation through leaf meal mixture on voluntary feed intake immune response and worm burden in Haemonchus contortus infected sheep
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Effect of condensed tannins supplementation through leaf meal mixture on voluntary feed intake immune response and worm burden in Haemonchus contortus infected sheep

机译：叶粉混合物补充单宁浓缩物对Contortus感染绵羊的自愿采食量免疫反应和蠕虫负荷的影响

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摘要

The study was carried out to assess the effect of condensed tannins (CT) supplementation through leaf meal mixture (LMM) on feed intake, humoral [Immunoglobulin G (IgG)], cell mediated immune response (CMI) and faecal egg counts in Haemonchus contortus infected sheep. Eighteen sheep were randomly divided into three groups (negative control—NC, infected control—C and Infected treatment—T) of six animals in each group in a completely randomized block design for a period of 90 days. Twelve H. contortus infected adult sheep were allocated into two equal groups C and T, supplemented with 0 and 1.5 % of CT, respectively. Six non-infected sheep of similar age and body weight of NC group were included in this study to compare their immune response with H. contortus C and CT supplemented T groups. Intake of dry matter and organic matter (g day−1 and % live weight) was statistically similar (P < 0.05) among the three groups. The anti-Haemonchus IgG and CMI response was higher in T group as compared to C group. The mean faecal egg counts was significantly (P < 0.001) higher in C group as compared to T group. It may be concluded that dietary supplementation of CT (1.5 %) through LMM improved humoral and CMI immune response and decreased worm load in H. contortus infected sheep.
机译：这项研究旨在评估通过叶粉混合物（LMM）补充单宁（CT）对饲料中摄入量，体液[免疫球蛋白G（IgG）]，细胞介导的免疫应答（CMI）和粪便弯曲菌粪便卵数的影响。被感染的绵羊。将18只绵羊按照完全随机区组设计随机分为三组（阴性对照组-NC，感染对照组-C和感染治疗-T），每组六只动物，共90天。将十二只经Contortus感染的成年绵羊分为C和T两个相等的组，分别补充0％和1.5％的CT。这项研究包括了六只年龄相同，体重相同的NC组的未感染绵羊，以比较它们与补充H. contortus C和CT的T组的免疫反应。在三组中，干物质和有机物质的摄入量（g·天 -1 和％活重）在统计学上相似（P <0.05）。与C组相比，T组的抗Haemonchus IgG和CMI反应更高。与T组相比，C组的粪便卵平均计数显着提高（P <0.001）。可以得出结论，通过LMM饮食中补充CT（1.5％）可以改善体液和CMI免疫反应，并减少感染Contortus的绵羊的蠕虫负荷。

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