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Evaluation of the Possible Utilization of 68Ga-DOTATOC in Diagnosis of Adenocarcinoma Breast Cancer

机译:68Ga-DOTATOC在腺癌乳腺癌诊断中的可能利用价值评估

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摘要

Objective(s):Studies have indicated advantageous properties of [DOTA-DPhe1, Tyr3] octreotide (DOTATOC) in tumor models and labeling with gallium. Breast cancer is the second leading cause of cancer mortality in women, and most of these cancers are often an adenocarcinoma. Due to the importance of target to non-target ratios in the efficacy of diagnosis, the pharmacokinetic of 68Ga-DOTATOC in an adenocarcinoma breast cancer animal model was studied in this research, and the optimized time for imaging was determined.
机译:目的:研究表明[DOTA-DPhe 1 ,Tyr 3 ]奥曲肽(DOTATOC)在肿瘤模型中和镓标记方面具有优越的性能。乳腺癌是女性癌症死亡的第二大主要原因,这些癌症中的大多数通常是腺癌。由于靶标与非靶标的比率在诊断功效中的重要性,因此研究了 68 Ga-DOTATOC在腺癌乳腺癌动物模型中的药代动力学,并优化了成像时间被确定。

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