• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Journal of Oral Microbiology >As-yet-uncultivated oral bacteria: breadth and association with oral and extra-oral diseases
【2h】

As-yet-uncultivated oral bacteria: breadth and association with oral and extra-oral diseases

机译：尚未培养的口腔细菌：广度以及与口腔和口腔外疾病的关联

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It has been shown that 40–60% of the bacteria found in different healthy and diseased oral sites still remain to be grown in vitro, phenotypically characterized, and formally named as species. The possibility exists that these as-yet-uncultivated bacteria play important ecological roles in oral bacterial communities and may participate in the pathogenesis of several oral infectious diseases. There is also a potential for these as-yet-uncultivated oral bacteria to take part in extra-oral infections. For a comprehensive characterization of physiological and pathogenic properties as well as antimicrobial susceptibility of individual bacterial species, strains need to be grown in pure culture. Advances in culturing techniques have allowed the cultivation of several oral bacterial taxa only previously known by a 16S rRNA gene sequence signature, and novel species have been proposed. There is a growing need for developing improved methods to cultivate and characterize the as-yet-uncultivated portion of the oral microbiome so as to unravel its role in health and disease.
机译：研究表明，在不同的健康和患病口腔部位发现的细菌中，仍有40-60％仍在体外生长，在表型上表征并正式命名为物种。这些尚未培养的细菌有可能在口腔细菌群落中发挥重要的生态作用，并可能参与多种口腔传染病的发病机制。这些尚未培养的口腔细菌也有可能参与口腔外感染。为了全面表征单个细菌物种的生理和致病特性以及对抗生素的敏感性，需要在纯培养物中培养菌株。培养技术的进步已经允许培养几种以前仅以16S rRNA基因序列特征已知的口腔细菌类群，并且已经提出了新物种。越来越需要开发改进的方法来培养和鉴定口腔微生物组的尚未培养的部分，以阐明其在健康和疾病中的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号