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Relative Afferent Pupillary Defects in Primary Open-Angle Glaucoma—Five Years Experience

机译:原发性开角型青光眼的相对传入瞳孔缺损—五年经验

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摘要

Afferent pupillary defects may accompany asymmetric primary open-angle glaucoma, though the exact incidence has not been reported. Charts were reviewed on 89 patients attending the Glaucoma/Uveitis Clinic at the North Carolina Memorial Hospital in Chapel Hill, North Carolina over a five-year period. All patients had primary open-angle glaucoma diagnosed by: (1) increased ocular tensions (22 mmHg) in the presence of open-anterior-chamber angles and (2) optic-nerve cupping and atrophy compatible with (3) pressure-dependent, visual-field loss. No subjects with secondary glaucomas, primary-angle-closure glaucoma, or ocular hypertension are included.The presence of the relative afferent pupillary defect was noted in 21 of 89 patients (23 percent). Sixteen of 70 black patients had relative afferent pupillary defect in the more severely affected eye, while five of 19 white patients demonstrated afferent pupils. Other demographic characteristics of this population are described. Two typical primary-open-angle glaucoma patients are discussed to demonstrate comparable changes within the optic nerves and Goldmann visual fields. The presence of the relative afferent pupillary defect best correlates with asymmetric, visual-field loss in the more severely affected eye.
机译:尽管尚未报道确切的发病率,但传入性瞳孔缺损可能伴有不对称原发性开角型青光眼。回顾了在五年期间在北卡罗来纳州教堂山北卡罗来纳州纪念医院的青光眼/葡萄膜炎诊所的89位患者的图表。所有患者均经以下诊断诊断为原发性开角型青光眼:(1)眼前房角张开时眼压升高(22 mmHg);(2)与(3)压力依赖性相适应的视神经拔罐和萎缩;视野损失。不包括继发性青光眼,原发性闭角型青光眼或高眼压症的受试者.89名患者中有21名(23%)发现存在相对传入瞳孔缺损。 70例黑人患者中有16例患病严重的眼睛有相对传入瞳孔缺损,而19例白人患者中有5例表现出瞳孔传入。描述了该人群的其他人口统计学特征。讨论了两名典型的原发性开角型青光眼患者,以证明视神经和Goldmann视野内的可比变化。相对传入瞳孔缺损的存在与受影响最严重的眼睛的不对称视野损失最相关。

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