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Assessment of Anti-inflammatory Activity of Taxus Baccata Linn. Bark Extract

机译:红豆杉抗炎活性的评估。树皮提取物

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摘要

Taxus baccata (L) known as Sthauneyaka in Sanskrit1 has wide range of biological activities including analgesic, anti-malarial, anti-rheumatic, sedative, anti-spasmodic, aphrodisiac and anti-asthmatic. In the present study, the dried and powdered bark of Taxus baccata (L) was extracted with 95% ethanol and ether at room temperature and screened for their anti--inflammatory activity by Carrageenan-induced paw edema method in rat. 95% ethanol extract exhibits potent anti-inflammatory activity at 200mg/kg four hours after administration in comparison with ether extract, as well reference standard, Aspirin. The observed pharmacological activities provide a scientific basis for the folklore use of the plant in treating acute inflammation.
机译:在梵语 1 中被称为Sthauneyaka的红豆杉具有广泛的生物活性,包括止痛,抗疟疾,抗风湿,镇静,抗痉挛,壮阳药和抗哮喘。在本研究中,在室温下用95%乙醇和乙醚提取紫杉干燥的粉末状树皮(L),并通过角叉菜胶诱导的爪水肿方法筛选其抗炎活性。与醚提取物以及参考标准品阿司匹林相比,在给药后四小时,95%乙醇提取物在200mg / kg时显示出有效的抗炎活性。观察到的药理活性为该植物在治疗急性炎症中的民间传说用途提供了科学依据。

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