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首页> 美国卫生研究院文献>AMIA Annual Symposium Proceedings >A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.
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A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.

机译：一种用于临床和利用研究的虚拟存储库方法：在乳腺摄影中的应用以替代国家数据库。

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摘要

A national mammography database was proposed, based on a centralized architecture for collecting, monitoring, and auditing mammography data. We have developed an alternative architecture relying on Internet-based distributed queries to heterogeneous databases. This architecture creates a "virtual repository", or a federated database which is constructed dynamically, for each query and makes use of data available in legacy systems. It allows the construction of custom-tailored databases at individual sites that can serve the dual purposes of providing data (a) to researchers through a common mammography repository and (b) to clinicians and administrators at participating institutions. We implemented this architecture in a prototype system at the Brigham and Women's Hospital to show its feasibility. Common queries are translated dynamically into database-specific queries, and the results are aggregated for immediate display or download by the user. Data reside in two different databases and consist of structured mammography reports, coded per BIRADS Standardized Mammography Lexicon, as well as pathology results. We prospectively collected data on 213 patients, and showed that our system can perform distributed queries effectively. We also implemented graphical exploratory analysis tools to allow visualization of results. Our findings indicate that the architecture is not only feasible, but also flexible and scaleable, constituting a good alternative to a national mammography database.
机译：提出了一个国家乳腺摄影数据库，该数据库基于用于收集，监视和审核乳腺摄影数据的集中式体系结构。我们已经开发了一种替代架构，该架构依赖于对异构数据库的基于Internet的分布式查询。这种体系结构为每个查询创建一个“虚拟存储库”或动态构建的联合数据库，并利用旧系统中的可用数据。它允许在各个站点上构建量身定制的数据库，这可以达到双重目的：（a）通过通用的乳房X线摄影库向研究人员提供数据，以及（b）向参与机构的临床医生和管理人员提供数据。我们在布里格姆妇女医院的原型系统中实现了该架构，以证明其可行性。常见查询会动态转换为特定于数据库的查询，并且会汇总结果以供用户立即显示或下载。数据位于两个不同的数据库中，由按BIRADS标准化乳腺摄影词典编码的结构化乳腺摄影报告以及病理结果组成。我们前瞻性地收集了213位患者的数据，并表明我们的系统可以有效地执行分布式查询。我们还实施了图形化探索性分析工具，以使结果可视化。我们的发现表明，该体系结构不仅可行，而且灵活且可扩展，构成了国家乳腺X线摄影数据库的良好替代方案。

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