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Constructing Clinical Decision Support Systems for Adverse Drug Event Prevention: A Knowledge-based Approach

机译:构建预防药物不良事件的临床决策支持系统:一种基于知识的方法

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摘要

A knowledge-based approach is proposed that is employed for the construction of a framework suitable for the management and effective use of knowledge on Adverse Drug Event (ADE) prevention. The framework has as its core part a Knowledge Base (KB) comprised of rule-based knowledge sources, that is accompanied by the necessary inference and query mechanisms to provide healthcare professionals and patients with decision support services in clinical practice, in terms of alerts and recommendations on preventable ADEs. The relevant Knowledge Based System (KBS) is developed in the context of the EU-funded research project PSIP (Patient Safety through Intelligent Procedures in Medication). In the current paper, we present the foundations of the framework, its knowledge model and KB structure, as well as recent progress as regards the population of the KB, the implementation of the KBS, and results on the KBS verification in decision support operation.
机译:提出了一种基于知识的方法,该方法可用于构建适合管理和有效利用有关不良药物事件(ADE)预防知识的框架。该框架的核心部分是知识库(KB),该知识库由基于规则的知识源组成,并配有必要的推理和查询机制,可为医疗保健专业人员和患者提供警报和预警方面的临床实践决策支持服务。关于可预防的ADE的建议。相关的基于知识的系统(KBS)是在欧盟资助的研究项目PSIP(通过药物智能程序实现患者安全)的背景下开发的。在本文中,我们介绍了该框架的基础,其知识模型和知识库结构,以及知识库的填充,知识库系统的实施以及在决策支持操作中知识库系统验证的结果方面的最新进展。

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