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首页> 美国卫生研究院文献>The American Journal of Tropical Medicine and Hygiene >Seroprevalence Survey of Chikungunya Virus in Bagan Panchor Malaysia
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Seroprevalence Survey of Chikungunya Virus in Bagan Panchor Malaysia

机译：马来西亚蒲甘潘乔基孔肯雅病毒的血清阳性率调查

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摘要

In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6%, and 17.5% of infected residents were asymptomatic. Arthralgia was reported up to 3 months after infection, but there were no reports of long-term functional dependence or depression. Symptomatic and seropositive residents were significantly more likely to live in the area with the most dense housing and commercial activities. CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak.
机译：2006年，亚洲基因型基孔肯雅病毒（CHIKV）暴发影响了马来西亚蒲甘潘乔村的200多人。一年后，进行了暴发后调查，以确定发作率，无症状率和感染后后遗症。将发现与近期中/东非基因型CHIKV爆发进行了比较。共有180名居民接受了急性症状，感染后生活质量和抑郁症状的采访。对来自72位居民的血清进行了CHIKV中和抗体测试。估计的发作率为55.6％，有17.5％的感染居民没有症状。据报道关节痛在感染后长达3个月，但没有长期功能依赖性或抑郁症的报道。有症状和血清反应阳性的居民更有可能居住在住房和商业活动最密集的地区。在蒲甘Panchor爆发期间，CHIKV具有很高的发病率和相当大的临床影响。

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