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Design and Implementation of a Laboratory-Based Drug Design and Synthesis Advanced Pharmacy Practice Experience

机译:基于实验室的药物设计与合成高级药学实践经验的设计与实现

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摘要

>Objective. To provide students with an opportunity to participate in medicinal chemistry research within the doctor of pharmacy (PharmD) curriculum.>Design. We designed and implemented a 3-course sequence in drug design or drug synthesis for pharmacy students consisting of a 1-month advanced elective followed by two 1-month research advanced pharmacy practice experiences (APPEs). To maximize student involvement, this 3-course sequence was offered to third-year and fourth-year students twice per calendar year.>Assessment. Students were evaluated based on their commitment to the project’s success, productivity, and professionalism. Students also evaluated the course sequence using a 14-item course evaluation rubric. Student feedback was overwhelmingly positive. Students found the experience to be a valuable component of their pharmacy curriculum.>Conclusion. We successfully designed and implemented a 3-course research sequence that allows PharmD students in the traditional 4-year program to participate in drug design and synthesis research. Students report the sequence enhanced their critical-thinking and problem-solving skills and helped them develop as independent learners. Based on the success achieved with this sequence, efforts are underway to develop research APPEs in other areas of the pharmaceutical sciences.
机译:>目标。为学生提供一次在药学博士(PharmD)课程范围内参与药物化学研究的机会。>设计。我们设计并实施了3门课程面向药学专业学生的药物设计或药物合成,包括1个月的高级选修课,然后是两个1个月的研究高级药学实践经验(APPE)。为了最大限度地提高学生的参与度,每个日历年向三年级和四年级的学生提供两次这三个课程的顺序。>评估。根据对项目成功,生产力和学习的承诺对学生进行评估。专业精神。学生还使用14个项目的评估规则评估了课程顺序。学生的反馈绝大多数是积极的。学生发现经验是他们药学课程的重要组成部分。>结论。我们成功设计并实施了一个3门课程的研究序列,使传统4年制课程中的PharmD学生可以参与药物设计。和综合研究。学生报告说,顺序训练提高了他们的批判性思维和解决问题的能力,并帮助他们成长为独立学习者。基于此序列所取得的成功,正在努力开发药物科学其他领域的研究APPE。

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