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Analysis of Blood Glucose Distribution Characteristics and Its Risk Factors among a Health Examination Population in Wuhu (China)

机译:芜湖市(中国)健康检查人群血糖分布特征及其危险因素分析

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摘要

Background: Diabetes mellitus (DM) and Impaired Fasting Glucose (IFG) represent serious threats to human health, and as a result, this study was aimed at understanding the blood glucose distribution characteristics and the risk factors among a large health examination population in China. Methods: An investigation with physical and biochemical examinations and questionnaires was conducted in the physical examination center from 2011 to 2014 and as a result 175,122 physical examination attendees were enrolled in this study. Multivariate logistic regression was used to explore the factors influencing blood sugar levels. Results: The rates of IFG and DM were 6.0% and 3.8%. Prevalence were 7.6%/5.1% in males and 5.1%/2.8% in females for IFG and DM, respectively. The prevalence of IFG and DM were thus higher in males than in females. In the normal group, except high density lipoprotein (HDL) that was significantly higher than in the IFG and DM group, the other indexes (age, body mass index (BMI), glucose (Glu), total cholesterol (TC) and total glycerides (TG) were lower than those in the IFG and DM group. The proportion of IFG and DM also increased with the increases in proportion of abnormal blood pressure, smoking and alcohol consumption. Multivariate logistic regression analysis showed that increasing age, high BMI, high TC, high TG and low HDL increased the risk of diabetes, while in males, in addition to the above factors, the smoking and drinking factors also increased the risk of diabetes. After the age of 65, the blood glucose level reached a peak in males, while in females, the increasing trends was on the rise. The inflexion age of the fast rise was younger in males than in females. Conclusion: The study population showed a high prevalence of DM and IFG among the adults. Regular physical examination for the early detection of diabetes is recommended in the high-risk population.
机译:背景:糖尿病(DM)和空腹血糖受损(IFG)对人类健康构成严重威胁,因此,本研究旨在了解中国大量健康检查人群的血糖分布特征和危险因素。方法:2011年至2014年,在体检中心进行了一次生化检查和问卷调查,共纳入175122名体检参与者。采用多元逻辑回归分析探讨影响血糖水平的因素。结果:IFG和DM的发生率分别为6.0%和3.8%。 IFG和DM的患病率分别为男性的7.6%/ 5.1%和女性的5.1%/ 2.8%。因此,男性的IFG和DM患病率高于女性。在正常组中,除了高密度脂蛋白(HDL)明显高于IFG和DM组外,其他指标(年龄,体重指数(BMI),葡萄糖(Glu),总胆固醇(TC)和总甘油酯(TG)低于IFG和DM组,IFG和DM的比例也随着异常血压,吸烟和饮酒的比例的增加而增加,多因素Logistic回归分析显示年龄增长,BMI高,高TC,高TG和低HDL增加了患糖尿病的风险,而在男性中,除上述因素外,吸烟和饮酒因素也增加了患糖尿病的风险,在65岁以后,血糖水平达到峰值。男性,而女性的增长趋势呈上升趋势,男性快速增长的屈曲年龄比女性年轻结论:研究人群显示成年人中DM和IFG的患病率较高。 Ť建议在高危人群中及早发现糖尿病。

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